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NCT02155257 · ClinicalTrials.gov registry record · Phase 4
Pain Expectations in Subjects With Osteoarthritis
A Phase 4 study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- Phase 4
- Development phase
- 30
- Enrollment target
NCT02155257: Completed Phase 4 study, sponsored by Wake Forest University Health Sciences.
NCT02155257 is a Phase 4 study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 30 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02155257, a Phase 4 study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 30 participants
- Enrollment target
Study Summary
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat temperatures in subjects with osteoarthritis of the knee or hip or healthy subjects for comparison. One of 3 possible treatment groups will be administered to qualifying subjects: (1) gabapentin, a medication that is commonly used to treat nerve pain, (2) modafinil, a medication that is commonly used to treat people with narcolepsy (a disorder that causes people to fall asleep) and (3) a placebo, which is an inactive substance, like a sugar pill, that is not thought to have any effect on your disease or condition
Primary Outcome
Resting pupil diameter will be measured using an infrared camera to obtain baseline measurements 2 hours after dosing subject pupil diameter measurements will be repeated
Interventions
- DRUG Placebo
- DRUG Modafinil
- DRUG Gabapentin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2014-07 |
| Est. Completion | 2017-10 |
| Phase | Phase 4 |
What the finished NCT02155257 record still lists
NCT02155257 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02155257 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02155257 about?
NCT02155257 is a clinical study titled "Pain Expectations in Subjects With Osteoarthritis". The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat temperatures in subjects with osteoarthritis of the knee or hip or healthy su...
What is the current status of trial NCT02155257?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2014-07. Estimated completion is 2017-10.
What interventions are being tested in trial NCT02155257?
The interventions under investigation include: Placebo (DRUG), Modafinil (DRUG), Gabapentin (DRUG).
Who is sponsoring clinical trial NCT02155257?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02155257's enrollment target sits among peer trials
30 1552nd of 2000 higher than 367 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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