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NCT02153814 · ClinicalTrials.gov registry record · NA

Endometrial Injury and in Vitro Fertilization Outcomes

A NA study, sponsored by Northwestern University.

Completed
Registry status
NA
Development phase
600
Enrollment target

NCT02153814: Completed NA study, sponsored by Northwestern University.

NCT02153814 is a NA study that has completed, run by Northwestern University. The registered enrollment target is 600 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02153814, a NA study, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
NA
Development phase
600 participants
Enrollment target

Study Summary

Infertility affects 1 in 7 couples worldwide. The most successful treatment is in vitro fertilization (IVF), a procedure where a woman's eggs are collected and fertilized with sperm to make embryos, which are then placed in the woman's uterus using a small catheter, a procedure called "embryo transfer." Unfortunately, pregnancy rates from IVF are less than 50%. Recently, several studies have shown dramatically improved pregnancy rates by grazing the innermost lining of the uterus (the endometrium) with a small flexible catheter weeks prior to embryo transfer. These studies were all performed outside the United States (U.S.) in women with multiple failed IVF attempts and did not investigate the mechanisms by which endometrial injury works. This study will be the first to evaluate the effect of endometrial injury on IVF success in all women undergoing IVF, including first IVF cycles, frozen embryo transfers, and donor eggs.

Interventions

  • PROCEDURE Sham procedure
  • PROCEDURE Endometrial Scratch

Trial Details

FieldValue
Enrollment Target 600 participants
Start Date 2014-08
Est. Completion 2018-12
Phase NA
Northwestern University

1,209 total trials

What the finished NCT02153814 record still lists

NCT02153814 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower).

The record links to 0 conditions, and to 2 interventions - of which Sham procedure is the first listed.

NCT02153814 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02153814 about?

NCT02153814 is a clinical study titled "Endometrial Injury and in Vitro Fertilization Outcomes". Infertility affects 1 in 7 couples worldwide. The most successful treatment is in vitro fertilization (IVF), a procedure where a woman's eggs are collected and fertilized with sperm to make embryos, which are then placed in the woman's uterus using a small catheter, a procedure called "embryo transf...

What is the current status of trial NCT02153814?

This trial is currently completed. It is a NA study. The enrollment target is 600 participants. The study started on 2014-08. Estimated completion is 2018-12.

What interventions are being tested in trial NCT02153814?

The interventions under investigation include: Sham procedure (PROCEDURE), Endometrial Scratch (PROCEDURE).

Who is sponsoring clinical trial NCT02153814?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02153814's enrollment target sits among peer trials

600 162nd of 2000 higher than 1,827 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02153814, the US trial registry maintained by the National Library of Medicine. NCT02153814 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.