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NCT02151396 · ClinicalTrials.gov registry record · Phase 3
Effect of Working Memory Training on ADHD Brain Function
A Phase 3 study of Attention-Deficit/Hyperactivity Disorder (Combined-subtype), sponsored by Hartford Hospital.
- Completed
- Registry status
- Phase 3
- Development phase
- 37
- Enrollment target
- 1
- Study location
NCT02151396: Completed Phase 3 study of Attention-Deficit/Hyperactivity Disorder (Combined-subtype), sponsored by Hartford Hospital.
NCT02151396 is a Phase 3 study of Attention-Deficit/Hyperactivity Disorder (Combined-subtype) that has completed, run by Hartford Hospital. The registered enrollment target is 37 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02151396, a Phase 3 study of Attention-Deficit/Hyperactivity Disorder (Combined-subtype), has completed, sponsored by Hartford Hospital.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 37 participants
- Enrollment target
- 1
- Study location
Study Summary
There is evidence both that computer-administered cognitive training can improve ADHD working memory deficits and that this type of training in non-ADHD enhances normal working memory ability by altering brain activity in prefrontal cortex and the parietal lobe. However, no study has characterized brain activity changes following working memory training in ADHD to understand what neural changes occur when cognitive deficits are remedied. This R21 exploratory study will examine the neural basis of cognitive training treatment gains in working memory, ADHD symptoms, and various other executive abilities. We will test the hypothesis that working memory training increases frontoparietal brain activation and examine other regions to see if there is any evidence for "neural compensation" (i.e., engagement of brain regions after training that are not normally recruited for task performance).
Primary Outcome
fMRI assessment of working memory-related brain function
Conditions Studied
Interventions
- BEHAVIORAL Working memory training
- DEVICE Functional magnetic resonance imaging (fMRI)
Study Locations (1)
Connecticut
- Olin Neurospychiatry Research Center - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2009-07 |
| Est. Completion | 2013-02 |
| Phase | Phase 3 |
What the finished NCT02151396 record still lists
NCT02151396 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Attention-Deficit/Hyperactivity Disorder (Combined-subtype) appearing as the primary indexed condition, and to 2 interventions - of which Working memory training is the first listed.
NCT02151396 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT02151396 about?
NCT02151396 is a clinical study titled "Effect of Working Memory Training on ADHD Brain Function". There is evidence both that computer-administered cognitive training can improve ADHD working memory deficits and that this type of training in non-ADHD enhances normal working memory ability by altering brain activity in prefrontal cortex and the parietal lobe. However, no study has characterized b...
What is the current status of trial NCT02151396?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 37 participants. The study started on 2009-07. Estimated completion is 2013-02.
What conditions does trial NCT02151396 study?
This clinical trial studies the following conditions: Attention-Deficit/Hyperactivity Disorder (Combined-subtype).
What interventions are being tested in trial NCT02151396?
The interventions under investigation include: Working memory training (BEHAVIORAL), Functional magnetic resonance imaging (fMRI) (DEVICE).
Who is sponsoring clinical trial NCT02151396?
This trial is sponsored by Hartford Hospital, which has 75 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02151396 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02151396's enrollment target sits among peer trials
37 1901st of 2000 higher than 100 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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