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NCT02151318 · ClinicalTrials.gov registry record
Culturing TM Cells From Primary Open-angle Glaucoma Patient Biopsies
A clinical trial, sponsored by University of South Florida.
- Completed
- Registry status
- 12
- Enrollment target
NCT02151318: Completed study, sponsored by University of South Florida.
NCT02151318 is a clinical trial that has completed, run by University of South Florida. The registered enrollment target is 12 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02151318 has completed, sponsored by University of South Florida.
- COMPLETED
- Registry status
- 12 participants
- Enrollment target
Study Summary
In this study, the investigators will collect tissue from patients undergoing trabeculectomy for primary open-angle glaucoma treatment. This tissue would normally be discarded. These trabecular meshwork (TM) cells can be cultured and used experimentally to better understand the mechanisms of glaucoma. These TM biopsies will be cultured on the same day as the trabeculectomy using established techniques.
Primary Outcome
TM cell biopsy samples from patients with glaucoma will be harvested and cultured in a laboratory setting to grow primary human TM cells. These cells will be used to test different medications, looking at the medications ability to reduce cellular pathologies commonly seen in TM tissue of patients with glaucoma. Pathologies include myocilin aggregation, and cell death. This will help researchers to determine the most effective compounds in treating glaucoma.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2014-12 |
| Est. Completion | 2016-11 |
What the finished NCT02151318 record still lists
NCT02151318 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 12 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT02151318 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02151318 about?
NCT02151318 is a clinical study titled "Culturing TM Cells From Primary Open-angle Glaucoma Patient Biopsies". In this study, the investigators will collect tissue from patients undergoing trabeculectomy for primary open-angle glaucoma treatment. This tissue would normally be discarded. These trabecular meshwork (TM) cells can be cultured and used experimentally to better understand the mechanisms of glaucom...
What is the current status of trial NCT02151318?
This trial is currently completed. The enrollment target is 12 participants. The study started on 2014-12. Estimated completion is 2016-11.
Who is sponsoring clinical trial NCT02151318?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
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