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NCT02147639 · ClinicalTrials.gov registry record · Phase 2

Effects of Sodium Nitrate on Blood Flow in Becker Muscular Dystrophy

A Phase 2 study of Becker Muscular Dystrophy, sponsored by Cedars-Sinai Medical Center.

Completed
Registry status
Phase 2
Development phase
19
Enrollment target
1
Study location

NCT02147639: Completed Phase 2 study of Becker Muscular Dystrophy, sponsored by Cedars-Sinai Medical Center.

NCT02147639 is a Phase 2 study of Becker Muscular Dystrophy that has completed, run by Cedars-Sinai Medical Center. The registered enrollment target is 19 participants, below the 1,395-participant average among 12 other Becker Muscular Dystrophy trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02147639, a Phase 2 study of Becker Muscular Dystrophy, has completed, sponsored by Cedars-Sinai Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
19 participants
Enrollment target
1
Study location

Study Summary

This study is intended to build on a growing body of literature showing a blood flow abnormality in patients with Becker muscular dystrophy. The investigators' laboratory recently showed that this blood flow abnormality could be corrected by a single oral dose of the drug Tadalafil (also known as Cialis). The investigators now wish to replicate these exciting results using a common nitric oxide donor (sodium nitrate).

Primary Outcome

Skeletal muscle blood flow regulation will be assessed at each visit by near infrared spectroscopy and Doppler ultrasound.

Conditions Studied

Becker Muscular Dystrophy

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT Sodium Nitrate
  • DIETARY_SUPPLEMENT Sodium Nitrate - double dose
  • PROCEDURE Increased exercise intensity

Study Locations (1)

California

  • Cedars-Sinai Heart Institute - Los Angeles

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2013-10
Est. Completion 2014-05
Phase Phase 2
Cedars-Sinai Medical Center

339 total trials

What the finished NCT02147639 record still lists

NCT02147639 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,395-participant average among 12 other Becker Muscular Dystrophy trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Becker Muscular Dystrophy appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT02147639 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT02147639 about?

NCT02147639 is a clinical study titled "Effects of Sodium Nitrate on Blood Flow in Becker Muscular Dystrophy". This study is intended to build on a growing body of literature showing a blood flow abnormality in patients with Becker muscular dystrophy. The investigators' laboratory recently showed that this blood flow abnormality could be corrected by a single oral dose of the drug Tadalafil (also known as Ci...

What is the current status of trial NCT02147639?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2013-10. Estimated completion is 2014-05.

What conditions does trial NCT02147639 study?

This clinical trial studies the following conditions: Becker Muscular Dystrophy.

What interventions are being tested in trial NCT02147639?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Sodium Nitrate (DIETARY_SUPPLEMENT), Sodium Nitrate - double dose (DIETARY_SUPPLEMENT), Increased exercise intensity (PROCEDURE).

Who is sponsoring clinical trial NCT02147639?

This trial is sponsored by Cedars-Sinai Medical Center, which has 339 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02147639 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Becker Muscular Dystrophy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02147639's enrollment target sits among peer trials

19 11th of 12 higher than 2 of 12 other Becker Muscular Dystrophy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Becker Muscular Dystrophy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT02147639, the US trial registry maintained by the National Library of Medicine. NCT02147639 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.