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NCT02143973 · ClinicalTrials.gov registry record · Phase 2

Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus

A Phase 2 study, sponsored by Trevi Therapeutics.

Completed
Registry status
Phase 2
Development phase
167
Enrollment target

NCT02143973: Completed Phase 2 study, sponsored by Trevi Therapeutics.

NCT02143973 is a Phase 2 study that has completed, run by Trevi Therapeutics. The registered enrollment target is 167 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (26% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02143973, a Phase 2 study, has completed, sponsored by Trevi Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
167 participants
Enrollment target

Study Summary

The primary objective of the study is to evaluate the overall safety of nalbuphine HCL ER tablets during a treatment period of up to 24 weeks.

Primary Outcome

The number of participants reporting at least one TEAE of a particular body system and preferred term are reported (incidence)

Interventions

  • DRUG nalbuphine HCl ER

Trial Details

FieldValue
Enrollment Target 167 participants
Start Date 2014-09
Est. Completion 2016-01
Phase Phase 2
Trevi Therapeutics

9 total trials

What the finished NCT02143973 record still lists

NCT02143973 is an interventional study that assigns participants to a tested intervention. The registered 167 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (26% higher).

The record links to 0 conditions, and to 1 intervention - of which nalbuphine HCl ER is the first listed.

NCT02143973 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02143973 about?

NCT02143973 is a clinical study titled "Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritus". The primary objective of the study is to evaluate the overall safety of nalbuphine HCL ER tablets during a treatment period of up to 24 weeks.

What is the current status of trial NCT02143973?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 167 participants. The study started on 2014-09. Estimated completion is 2016-01.

What interventions are being tested in trial NCT02143973?

The interventions under investigation include: nalbuphine HCl ER (DRUG).

Who is sponsoring clinical trial NCT02143973?

This trial is sponsored by Trevi Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02143973's enrollment target sits among peer trials

167 406th of 2000 higher than 1,595 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02143973, the US trial registry maintained by the National Library of Medicine. NCT02143973 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.