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NCT02140554 · ClinicalTrials.gov registry record · Phase 1

A Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell Disease

A Phase 1 study, sponsored by Genetix Biotherapeutics.

Completed
Registry status
Phase 1
Development phase
54
Enrollment target

NCT02140554 is a Phase 1 study that has completed, run by Genetix Biotherapeutics. The registered enrollment target is 54 participants.

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The verdict

NCT02140554, a Phase 1 study, has completed, sponsored by Genetix Biotherapeutics.

COMPLETED
Registry status
Phase 1
Development phase
54 participants
Enrollment target

Study Summary

This is a non-randomized, open label, multi-site, single dose, Phase 1/2 study in approximately 50 adults and adolescents with severe SCD. The study will evaluate hematopoietic stem cell and progenitor stem cell (collectively referred to as hematopoietic stem and progenitor cells or HSPCs) transplantation using lovo-cel.

Interventions

  • GENETIC lovo-cel

Trial Details

FieldValue
Enrollment Target 54 participants
Start Date 2015-02-02
Est. Completion 2024-01-30
Phase Phase 1

Sponsor

Genetix Biotherapeutics

12 total trials

What the Registry Record Tells You About NCT02140554

The ClinicalTrials.gov registry entry for NCT02140554 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genetix Biotherapeutics, which has 12 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which lovo-cel is the first listed.

NCT02140554 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02140554 about?

NCT02140554 is a clinical study titled "A Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell Disease". This is a non-randomized, open label, multi-site, single dose, Phase 1/2 study in approximately 50 adults and adolescents with severe SCD. The study will evaluate hematopoietic stem cell and progenitor stem cell (collectively referred to as hematopoietic stem and progenitor cells or HSPCs) transplan...

What is the current status of trial NCT02140554?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 54 participants. The study started on 2015-02-02. Estimated completion is 2024-01-30.

What interventions are being tested in trial NCT02140554?

The interventions under investigation include: lovo-cel (GENETIC).

Who is sponsoring clinical trial NCT02140554?

This trial is sponsored by Genetix Biotherapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.