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NCT02138214 · ClinicalTrials.gov registry record · Phase 2
Central Neck Dissection in Patients With Clinical Node Negative Thyroid Cancer
A Phase 2 study of Stage I Papillary Thyroid Cancer and Stage II Papillary Thyroid Cancer, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- Phase 2
- Development phase
- 117
- Enrollment target
- 1
- Study location
NCT02138214: Completed Phase 2 study of Stage I Papillary Thyroid Cancer and Stage II Papillary Thyroid Cancer, sponsored by University of Wisconsin, Madison.
NCT02138214 is a Phase 2 study of Stage I Papillary Thyroid Cancer and Stage II Papillary Thyroid Cancer that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 117 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (12% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02138214, a Phase 2 study of Stage I Papillary Thyroid Cancer and Stage II Papillary Thyroid Cancer, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 117 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase II trial studies how well thyroid gland removal with or without central lymph node dissection works in treating patients with thyroid cancer or suspected thyroid cancer that has not spread to the lymph nodes (randomized into Arms I and II). Arms I and II are compared to a standard of care (SOC) Arm III to enable comparison of quality of life among various surgical treatments. Currently, the standard treatment for thyroid cancer is total thyroidectomy, or complete removal of the thyroid. The lymph nodes in the central part of the neck may also be surgically removed, called central lymph node dissection. Prophylactic removal of the lymph nodes may increase the risk of life-threatening complications, and may reduce post-surgery quality of life. It may also prevent the cancer from returning and reduce the need for additional surgery. It is not yet known whether recurrence rates and complication levels are lower after thyroid gland removal alone or with central lymph node dissection.
Primary Outcome
Rate of transient hypoparathyroidism will be assessed in terms of percentage of participants with day 1 serum PTH level of \< 10 pg/ml.
Conditions Studied
Interventions
- PROCEDURE Thyroidectomy
- PROCEDURE entral lymph node dissection (CLND)
- OTHER Quality-of-life assessment
Study Locations (1)
Wisconsin
- University of Wisconsin - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 117 participants |
| Start Date | 2014-06-06 |
| Est. Completion | 2020-10-26 |
| Phase | Phase 2 |
What the finished NCT02138214 record still lists
NCT02138214 is an interventional study that assigns participants to a tested intervention. The registered 117 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (12% lower).
The record links to 3 conditions, with Stage I Papillary Thyroid Cancer appearing as the primary indexed condition, and to 3 interventions - of which Thyroidectomy is the first listed.
NCT02138214 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT02138214 about?
NCT02138214 is a clinical study titled "Central Neck Dissection in Patients With Clinical Node Negative Thyroid Cancer". This phase II trial studies how well thyroid gland removal with or without central lymph node dissection works in treating patients with thyroid cancer or suspected thyroid cancer that has not spread to the lymph nodes (randomized into Arms I and II). Arms I and II are compared to a standard of care...
What is the current status of trial NCT02138214?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 117 participants. The study started on 2014-06-06. Estimated completion is 2020-10-26.
What conditions does trial NCT02138214 study?
This clinical trial studies the following conditions: Stage I Papillary Thyroid Cancer, Stage II Papillary Thyroid Cancer, Stage III Papillary Thyroid Cancer.
What interventions are being tested in trial NCT02138214?
The interventions under investigation include: Thyroidectomy (PROCEDURE), entral lymph node dissection (CLND) (PROCEDURE), Quality-of-life assessment (OTHER).
Who is sponsoring clinical trial NCT02138214?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02138214 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02138214's enrollment target sits among peer trials
117 623rd of 2000 higher than 1,378 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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