Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02137642 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation
A Phase 1 study, sponsored by Motus Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
NCT02137642: Completed Phase 1 study, sponsored by Motus Therapeutics.
NCT02137642 is a Phase 1 study that has completed, run by Motus Therapeutics. The registered enrollment target is 18 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02137642, a Phase 1 study, has completed, sponsored by Motus Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic motor and sensory effects in patients with chronic constipation.
Primary Outcome
Change from baseline HAPC
Interventions
- DRUG Placebo
- DRUG RM-131
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2014-08 |
| Est. Completion | 2014-11 |
| Phase | Phase 1 |
What the finished NCT02137642 record still lists
NCT02137642 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02137642 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02137642 about?
NCT02137642 is a clinical study titled "Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation". The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic motor and sensory effects in patients with chronic constipation.
What is the current status of trial NCT02137642?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2014-08. Estimated completion is 2014-11.
What interventions are being tested in trial NCT02137642?
The interventions under investigation include: Placebo (DRUG), RM-131 (DRUG).
Who is sponsoring clinical trial NCT02137642?
This trial is sponsored by Motus Therapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02137642's enrollment target sits among peer trials
18 1720th of 2000 higher than 216 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01245179 · 18 participants · Phase 1
Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease
- NCT01999361 · 18 participants · NA
Prevention of de Novo Allosensitization in Islet Transplant Recipients Following Complete Graft Loss
- NCT02359825 · 18 participants · Phase 1
Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function
- NCT02870244 · 18 participants · Phase 1
Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia