Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02132845 · ClinicalTrials.gov registry record · NA

Next Generation Sequence Target-Directed Therapy in Treating Patients With Cancer

A NA study, sponsored by Fox Chase Cancer Center.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT02132845: Completed NA study, sponsored by Fox Chase Cancer Center.

NCT02132845 is a NA study that has completed, run by Fox Chase Cancer Center. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02132845, a NA study, has completed, sponsored by Fox Chase Cancer Center.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

This randomized clinical trial studies how well next generation sequence target-directed therapy works in treating patients with cancer. Next generation sequencing is a test that screens for mutations to cancer related genes. Target-directed therapy is a type of treatment that uses drugs or other substances to identify and attack specific types of cancer cells that may have less harm to normal cells. Next generation sequencing may help identify these specific types of cancer cells.

Primary Outcome

The overall (composite) response rate will be defined by tumor response rate according to RECIST 1.1 or by tumor marker response for patients without measurable disease defined by RECIST 1.1. Tumor marker response will be quantified as a 50% reduction in the marker of interest, when compared to baseline, without any radiographic evidence of progressive disease.

Interventions

  • OTHER laboratory biomarker analysis
  • OTHER cytology specimen collection procedure
  • DRUG targeted therapy
  • PROCEDURE therapeutic procedure

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2016-03-17
Est. Completion 2018-05-10
Phase NA
Fox Chase Cancer Center

183 total trials

What the finished NCT02132845 record still lists

NCT02132845 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT02132845 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02132845 about?

NCT02132845 is a clinical study titled "Next Generation Sequence Target-Directed Therapy in Treating Patients With Cancer". This randomized clinical trial studies how well next generation sequence target-directed therapy works in treating patients with cancer. Next generation sequencing is a test that screens for mutations to cancer related genes. Target-directed therapy is a type of treatment that uses drugs or other su...

What is the current status of trial NCT02132845?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2016-03-17. Estimated completion is 2018-05-10.

What interventions are being tested in trial NCT02132845?

The interventions under investigation include: laboratory biomarker analysis (OTHER), cytology specimen collection procedure (OTHER), targeted therapy (DRUG), therapeutic procedure (PROCEDURE).

Who is sponsoring clinical trial NCT02132845?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02132845's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02132845, the US trial registry maintained by the National Library of Medicine. NCT02132845 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.