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NCT02132182 · ClinicalTrials.gov registry record
Monocyte Phenotypic and Functional Differences
A clinical trial, sponsored by Duke University.
- Completed
- Registry status
- 15
- Enrollment target
NCT02132182: Completed study, sponsored by Duke University.
NCT02132182 is a clinical trial that has completed, run by Duke University. The registered enrollment target is 15 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02132182 has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- 15 participants
- Enrollment target
Study Summary
The purpose of this study is to identify phenotypic (cell surface receptor expression) and functional differences in monocyte populations in humans with osteosarcoma as compared to published historical data on normal human monocyte values. The biologic similarity between canine and human osteosarcoma makes it a disease model that holds promise for translational research possibilities. The phenotypic and functional differences the investigators expect to find in canine and human monocytes between normal and osteosarcoma subjects in this pilot work will allow us to launch a program of investigations to further their understanding as to what characteristics are associated with improved survival in canine and human osteosarcoma. Such data will represent the foundation upon which the investigators can plan future investigations designed to exploit the potential anti-tumor capabilities of monocytes and macrophages in canine and human osteosarcoma.
Primary Outcome
We will characterize the phenotypic differences demonstrated by variations in cell surface receptor expression, such as CCR2, CCR7 and CD32, between normal monocytes and monocytes in osteosarcoma patients.
Interventions
- BIOLOGICAL Blood draw
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2014-10 |
| Est. Completion | 2017-03-23 |
What the finished NCT02132182 record still lists
NCT02132182 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 15 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Blood draw is the first listed.
NCT02132182 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02132182 about?
NCT02132182 is a clinical study titled "Monocyte Phenotypic and Functional Differences". The purpose of this study is to identify phenotypic (cell surface receptor expression) and functional differences in monocyte populations in humans with osteosarcoma as compared to published historical data on normal human monocyte values. The biologic similarity between canine and human osteosarco...
What is the current status of trial NCT02132182?
This trial is currently completed. The enrollment target is 15 participants. The study started on 2014-10. Estimated completion is 2017-03-23.
What interventions are being tested in trial NCT02132182?
The interventions under investigation include: Blood draw (BIOLOGICAL).
Who is sponsoring clinical trial NCT02132182?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
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