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NCT02131376 · ClinicalTrials.gov registry record · NA
Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy
A NA study, sponsored by Indiana University.
- Terminated
- Registry status
- NA
- Development phase
- 26
- Enrollment target
NCT02131376: Clinical Trial NA study, sponsored by Indiana University.
NCT02131376 is a NA study that was terminated before completion, run by Indiana University. The registered enrollment target is 26 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02131376, a NA study, was terminated before completion, sponsored by Indiana University.
- TERMINATED
- Registry status
- NA
- Development phase
- 26 participants
- Enrollment target
Study Summary
Preserving kidney function during removal of a kidney tumor is becoming increasingly important as rates of chronic kidney disease increase. A novel modifiable factor (suture closure of the defect caused by tumor removal) was discovered on retrospective studies to account for nearly two-thirds of the 15% volume loss commonly seen in operated kidneys. We hypothesize that a randomized controlled surgical trial will show that omitting the suture closure both preserves renal function and will not lead to unreasonable postoperative complications.
Primary Outcome
% loss in renal volume (cm3) of the operated kidney (post-operative CT at 4 mo vs. - pre-operative CT) using Phillips IntelliSpace portal semi-automated segmentation algorithm.
Interventions
- PROCEDURE Non-renorrhaphy
- PROCEDURE Renorrhaphy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2014-05-09 |
| Est. Completion | 2019-08-29 |
| Phase | NA |
Why NCT02131376 stopped before completion
NCT02131376 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Non-renorrhaphy is the first listed.
NCT02131376 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02131376 about?
NCT02131376 is a clinical study titled "Investigating a Novel Modifiable Factor Affecting Renal Function After Partial Nephrectomy: Cortical Renorrhaphy". Preserving kidney function during removal of a kidney tumor is becoming increasingly important as rates of chronic kidney disease increase. A novel modifiable factor (suture closure of the defect caused by tumor removal) was discovered on retrospective studies to account for nearly two-thirds of the...
What is the current status of trial NCT02131376?
This trial is currently terminated. It is a NA study. The enrollment target is 26 participants. The study started on 2014-05-09. Estimated completion is 2019-08-29.
What interventions are being tested in trial NCT02131376?
The interventions under investigation include: Non-renorrhaphy (PROCEDURE), Renorrhaphy (PROCEDURE).
Who is sponsoring clinical trial NCT02131376?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02131376's enrollment target sits among peer trials
26 1710th of 2000 higher than 289 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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