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NCT02129712 · ClinicalTrials.gov registry record · NA
Neuroplasticity-Based Cognitive Remediation for Pediatric Brain Tumor Survivors
A NA study, sponsored by Vanderbilt University.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT02129712: Completed NA study, sponsored by Vanderbilt University.
NCT02129712 is a NA study that has completed, run by Vanderbilt University. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02129712, a NA study, has completed, sponsored by Vanderbilt University.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
This research will leverage novel pilot research conducted by the investigators to take important first steps in addressing neurocognitive late effects by intervening early, during treatment, with a promising computerized cognitive remediation program to prevent the downward trajectory of neurocognitive function experienced by pediatric brain tumor survivors. Specifically, we propose to test the feasibility, acceptability, and initial proof of concept of a neuroplasticity-based adaptive cognitive training program (Cogmed) to train working memory (WM) and attention in newly diagnosed youth with a brain tumor. Further, we will test the feasibility of using this intervention in a true prospective design beginning pre-surgery to examine the effects of this intervention in deflecting the downward trajectory of cognitive function in children with brain tumors during treatment. We will also use functional neuroimaging (near infrared spectroscopy - "NIRS") to examine the effects of this program on brain activation in frontal regions that are affected by treatment. Findings from this pilot study will inform the development of a large multi-site randomized efficacy trial to test an individualized cognitive training program. Aim 1. To test the feasibility and acceptability of enrolling youth (7 to 16 years-old) with newly diagnosed brain tumors at time of diagnosis, following patients for 10 weeks, delivering the Cogmed computer-based training program in a randomized trial at 10-weeks post-diagnosis, and following patients to 1 year post-diagnosis. Aim 2. To test the initial acceptability and efficacy of the Cogmed training program on cognitive function in newly diagnosed pediatric brain tumor patients.
Interventions
- BEHAVIORAL Cognitive training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2014-02-01 |
| Est. Completion | 2017-12-31 |
| Phase | NA |
What the finished NCT02129712 record still lists
NCT02129712 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Cognitive training is the first listed.
NCT02129712 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02129712 about?
NCT02129712 is a clinical study titled "Neuroplasticity-Based Cognitive Remediation for Pediatric Brain Tumor Survivors". This research will leverage novel pilot research conducted by the investigators to take important first steps in addressing neurocognitive late effects by intervening early, during treatment, with a promising computerized cognitive remediation program to prevent the downward trajectory of neurocogni...
What is the current status of trial NCT02129712?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2014-02-01. Estimated completion is 2017-12-31.
What interventions are being tested in trial NCT02129712?
The interventions under investigation include: Cognitive training (BEHAVIORAL).
Who is sponsoring clinical trial NCT02129712?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02129712's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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