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NCT02120898 · ClinicalTrials.gov registry record · Phase 3

A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses

A Phase 3 study, sponsored by Actavis.

Completed
Registry status
Phase 3
Development phase
467
Enrollment target

NCT02120898: Completed Phase 3 study, sponsored by Actavis.

NCT02120898 is a Phase 3 study that has completed, run by Actavis. The registered enrollment target is 467 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02120898, a Phase 3 study, has completed, sponsored by Actavis.

COMPLETED
Registry status
Phase 3
Development phase
467 participants
Enrollment target

Study Summary

The purpose of this study it so compare the safety and efficacy profiles of a generic imiquimod 2.5% cream to the reference listed Zyclara® (imiquimod) cream in the treatment of actinic keratosis (AK).

Primary Outcome

Complete clearance rate (treatment success) was defined as the percentage of participants in each treatment group with a count of zero actinic keratosis (AK) lesions in the treatment area at Week 14. All AKs (baseline and new lesions) independent of size within the treatment area were included in the efficacy lesion count. The AK clearance rate for a participant was calculated as follows: {1 - \[ (number of AK lesions at Week 14) / (number of AK lesions at Baseline)\]} \* 100.

Interventions

  • DRUG Imiquimod
  • DRUG Vehicle Cream
  • DRUG Zyclara®

Trial Details

FieldValue
Enrollment Target 467 participants
Start Date 2013-10-10
Est. Completion 2014-04-30
Phase Phase 3
Actavis

79 total trials

What the finished NCT02120898 record still lists

NCT02120898 is an interventional study that assigns participants to a tested intervention. The registered 467 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 3 interventions - of which Imiquimod is the first listed.

NCT02120898 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02120898 about?

NCT02120898 is a clinical study titled "A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses". The purpose of this study it so compare the safety and efficacy profiles of a generic imiquimod 2.5% cream to the reference listed Zyclara® (imiquimod) cream in the treatment of actinic keratosis (AK).

What is the current status of trial NCT02120898?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 467 participants. The study started on 2013-10-10. Estimated completion is 2014-04-30.

What interventions are being tested in trial NCT02120898?

The interventions under investigation include: Imiquimod (DRUG), Vehicle Cream (DRUG), Zyclara® (DRUG).

Who is sponsoring clinical trial NCT02120898?

This trial is sponsored by Actavis, which has 79 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02120898's enrollment target sits among peer trials

467 816th of 2000 higher than 1,185 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02120898, the US trial registry maintained by the National Library of Medicine. NCT02120898 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.