Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02116309 · ClinicalTrials.gov registry record · NA
Randomized Trial of Rectal Indomethacin and Papillary Spray of Epinephrine Versus Rectal Indomethacin to Prevent Post-ERCP Pancreatitis
A NA study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 948
- Enrollment target
NCT02116309: Completed NA study, sponsored by Johns Hopkins University.
NCT02116309 is a NA study that has completed, run by Johns Hopkins University. The registered enrollment target is 948 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02116309, a NA study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 948 participants
- Enrollment target
Study Summary
This research is being done to see if using a combination of rectal indomethacin and epinephrine spray during endoscopy, can prevent pancreatitis that may occur after ERCP (a type of gastrointestinal endoscopy).
Primary Outcome
The primary outcome variable of interest is the incidence of post ERCP pancreatitis (PEP) as defined by the consensus guidelines as 1) New or increased abdominal pain that is clinically consistent with a syndrome of acute pancreatitis and 2) amylase or lipase ≥ 3x the upper limit of normal 24 hours after the procedure and 3) Hospitalization or prolongation of existing hospitalization for at least 2 days.
Interventions
- DRUG Epinephrine
- DRUG Rectal Indomethacin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 948 participants |
| Start Date | 2014-08 |
| Est. Completion | 2016-12-02 |
| Phase | NA |
What the finished NCT02116309 record still lists
NCT02116309 is an interventional study that assigns participants to a tested intervention. The registered 948 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 2 interventions - of which Epinephrine is the first listed.
NCT02116309 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02116309 about?
NCT02116309 is a clinical study titled "Randomized Trial of Rectal Indomethacin and Papillary Spray of Epinephrine Versus Rectal Indomethacin to Prevent Post-ERCP Pancreatitis". This research is being done to see if using a combination of rectal indomethacin and epinephrine spray during endoscopy, can prevent pancreatitis that may occur after ERCP (a type of gastrointestinal endoscopy).
What is the current status of trial NCT02116309?
This trial is currently completed. It is a NA study. The enrollment target is 948 participants. The study started on 2014-08. Estimated completion is 2016-12-02.
What interventions are being tested in trial NCT02116309?
The interventions under investigation include: Epinephrine (DRUG), Rectal Indomethacin (DRUG).
Who is sponsoring clinical trial NCT02116309?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02116309's enrollment target sits among peer trials
948 123rd of 2000 higher than 1,878 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT04895709 · 949 participants · Phase 1
A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors
- NCT06087224 · 947 participants · NA
The TELENEO Trial: A Multicenter Trial of Telemedicine for Advanced Neonatal Resuscitations in Community Hospitals
- NCT03784924 · 950 participants
EDRN Prostate MRI Biomarker Study
- NCT04180930 · 950 participants
An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia