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NCT02109809 · ClinicalTrials.gov registry record · NA
Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell Transplant
A NA study, sponsored by Wake Forest University Health Sciences.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT02109809: Clinical Trial NA study, sponsored by Wake Forest University Health Sciences.
NCT02109809 is a NA study that was terminated before completion, run by Wake Forest University Health Sciences. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02109809, a NA study, was terminated before completion, sponsored by Wake Forest University Health Sciences.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
This phase I trial studies the side effects and best dose of low-dose total lymphoid irradiation (LD-TLI) in treating patients with chronic graft-versus-host disease that has not responded to treatment with steroids. LD-TLI is a procedure in which all of the body's major lymph nodes are treated with small doses of radiation in order to reset the dysfunctional immune system. LD-TLI may work as a treatment for graft-versus-host disease caused by a bone marrow or stem cell transplant.
Primary Outcome
Toxicities (grade 2 and higher) will be reported as number of occurrences.
Interventions
- OTHER laboratory biomarker analysis
- OTHER questionnaire administration
- RADIATION total nodal irradiation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2014-07 |
| Est. Completion | 2016-09 |
| Phase | NA |
Why NCT02109809 stopped before completion
NCT02109809 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which laboratory biomarker analysis is the first listed.
NCT02109809 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02109809 about?
NCT02109809 is a clinical study titled "Low-Dose Total Lymphoid Irradiation in Treating Patients With Refractory Chronic Graft-versus-Host Disease After Donor Stem Cell Transplant". This phase I trial studies the side effects and best dose of low-dose total lymphoid irradiation (LD-TLI) in treating patients with chronic graft-versus-host disease that has not responded to treatment with steroids. LD-TLI is a procedure in which all of the body's major lymph nodes are treated with...
What is the current status of trial NCT02109809?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2014-07. Estimated completion is 2016-09.
What interventions are being tested in trial NCT02109809?
The interventions under investigation include: laboratory biomarker analysis (OTHER), questionnaire administration (OTHER), total nodal irradiation (RADIATION).
Who is sponsoring clinical trial NCT02109809?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02109809's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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