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NCT02097953 · ClinicalTrials.gov registry record · Early Phase 1
Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin
A Early Phase 1 study, sponsored by University of Utah.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 12
- Enrollment target
NCT02097953: Completed Early Phase 1 study, sponsored by University of Utah.
NCT02097953 is a Early Phase 1 study that has completed, run by University of Utah. The registered enrollment target is 12 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02097953, a Early Phase 1 study, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 12 participants
- Enrollment target
Study Summary
The purpose of this study is to understand how an antibiotic, rifampin, may change the blood levels of another antibiotic, daptomycin, in the body. In addition, the effect of polymorphisms in P-glycoprotein (a protein involved in the removal of daptomycin from the body) on the blood levels of daptomycin will be evaluated. The hypotheses are that rifampin will decrease the blood levels of daptomycin and that the effect will be greater for certain P-glycoprotein polymorphisms.
Primary Outcome
Total, renal, and non-renal clearance of daptomycin before and after administration of rifampin
Interventions
- DRUG Rifampin
- DRUG Daptomycin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2014-05 |
| Est. Completion | 2016-07 |
| Phase | Early Phase 1 |
What the finished NCT02097953 record still lists
NCT02097953 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 2 interventions - of which Rifampin is the first listed.
NCT02097953 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02097953 about?
NCT02097953 is a clinical study titled "Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin". The purpose of this study is to understand how an antibiotic, rifampin, may change the blood levels of another antibiotic, daptomycin, in the body. In addition, the effect of polymorphisms in P-glycoprotein (a protein involved in the removal of daptomycin from the body) on the blood levels of daptom...
What is the current status of trial NCT02097953?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 12 participants. The study started on 2014-05. Estimated completion is 2016-07.
What interventions are being tested in trial NCT02097953?
The interventions under investigation include: Rifampin (DRUG), Daptomycin (DRUG).
Who is sponsoring clinical trial NCT02097953?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02097953's enrollment target sits among peer trials
12 1530th of 2000 higher than 401 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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