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NCT02090894 · ClinicalTrials.gov registry record · NA
Effect of Dermal Rejuvenation on the UVB Response of Geriatric Skin
A NA study, sponsored by Indiana University.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
NCT02090894 is a NA study that has completed, run by Indiana University. The registered enrollment target is 11 participants.
The verdict
NCT02090894, a NA study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
Study Summary
The objective of this study is to examine the ability of dermal rejuvenation therapies to protect geriatric skin from ultraviolet light (UVB)-induced carcinogenesis. Skin cancers (including basal cell carcinoma and squamous cell carcinoma) are the most common types of malignancy and are related to UVB exposure in sunlight. UVB-irradiation of skin causes specific DNA damage to keratinocytes that can lead to cancer-causing mutations if they are allowed to persist in proliferating cells. Moreover, the incidence of skin cancers is much greater in elderly over younger individuals. The objective of the present study is to build upon our previous data and test the effect of a non ablative Nd:YAG laser (LaserGenesis) of a localized area of skin on dermal IGF-1 production and UVB-mediated keratinocyte effects. Treatment of skin using a non ablative high-peak power microsecond pulsed 1064 nm Nd:YAG laser (Cutera's LaserGenesisTM laser) leads to papillary dermal heating. The laser targets the microvasculature and stimulates collagen production while protecting the epidermis. Generally, Laser Genesis is used clinically to improve irregularities in the contour, texture, and color of the skin. Laser Genesis is also used to help treat photoaging by increasing collagen formation, suggesting that it stimulates fibroblast activity and thus possibly increases levels of protective IGF-1.
Interventions
- DEVICE UV Light (Laser Genesis)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2011-03 |
| Est. Completion | 2016-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02090894
The ClinicalTrials.gov registry entry for NCT02090894 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which UV Light (Laser Genesis) is the first listed.
NCT02090894 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02090894 about?
NCT02090894 is a clinical study titled "Effect of Dermal Rejuvenation on the UVB Response of Geriatric Skin". The objective of this study is to examine the ability of dermal rejuvenation therapies to protect geriatric skin from ultraviolet light (UVB)-induced carcinogenesis. Skin cancers (including basal cell carcinoma and squamous cell carcinoma) are the most common types of malignancy and are related to U...
What is the current status of trial NCT02090894?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2011-03. Estimated completion is 2016-12.
What interventions are being tested in trial NCT02090894?
The interventions under investigation include: UV Light (Laser Genesis) (DEVICE).
Who is sponsoring clinical trial NCT02090894?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
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