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NCT02089386 · ClinicalTrials.gov registry record · Early Phase 1
Tamoxifen to Treat Barrett's Metaplasia
A Early Phase 1 study, sponsored by Washington University School of Medicine.
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 7
- Enrollment target
NCT02089386: Clinical Trial Early Phase 1 study, sponsored by Washington University School of Medicine.
NCT02089386 is a Early Phase 1 study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 7 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02089386, a Early Phase 1 study, was terminated before completion, sponsored by Washington University School of Medicine.
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
Treat Barrett's esophagus (BE) patients with tamoxifen to Barrett's metaplasia as measured by changes in Barrett's esophagus appearance by endoscopy and histology as well as changes in SOX2 and CDX2.
Primary Outcome
The biopsy procedures with 4 quadrant biopsies/2 cm for histology and additional biopsies for freezing for macromolecular analysis to assess the preliminary diagnostic value of this marker pair in identifying levels of metaplasia in BE and as an indicator of response to tamoxifen treatment. The tissue from the two endoscopic procedures will be assessed for changes in the following related to tamoxifen therapy.
Interventions
- DRUG Tamoxifen
- PROCEDURE Endoscopy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2014-07-09 |
| Est. Completion | 2016-06-21 |
| Phase | Early Phase 1 |
Why NCT02089386 stopped before completion
NCT02089386 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 2 interventions - of which Tamoxifen is the first listed.
NCT02089386 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02089386 about?
NCT02089386 is a clinical study titled "Tamoxifen to Treat Barrett's Metaplasia". Treat Barrett's esophagus (BE) patients with tamoxifen to Barrett's metaplasia as measured by changes in Barrett's esophagus appearance by endoscopy and histology as well as changes in SOX2 and CDX2.
What is the current status of trial NCT02089386?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 7 participants. The study started on 2014-07-09. Estimated completion is 2016-06-21.
What interventions are being tested in trial NCT02089386?
The interventions under investigation include: Tamoxifen (DRUG), Endoscopy (PROCEDURE).
Who is sponsoring clinical trial NCT02089386?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02089386's enrollment target sits among peer trials
7 1825th of 2000 higher than 156 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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