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NCT02087553 · ClinicalTrials.gov registry record
PICU Transfusion Study: Harmful Effects of Red Blood Cell Transfusions
A clinical trial, sponsored by Columbia University.
- Completed
- Registry status
- 120
- Enrollment target
NCT02087553: Completed study, sponsored by Columbia University.
NCT02087553 is a clinical trial that has completed, run by Columbia University. The registered enrollment target is 120 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02087553 has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- 120 participants
- Enrollment target
Study Summary
The investigators hypothesize that the storage-damaged red cells are responsible for some of the adverse effects of transfusion. In this observational study, the investigators will measure various laboratory parameters both before and after transfusion in a pediatric intensive care unit to determine at what duration of storage is there laboratory evidence of refrigerator storage damage. The investigators hypothesize that increasing storage time of packed red blood cells (PRBCs) transfused will be associated with increasing non-transferrin-bound iron (NTBI), pro-inflammatory cytokine concentrations, and enhanced microbial growth in vitro in pediatric patients.
Primary Outcome
Circulating non-transferrin-bound iron level post-transfusion (taken between 2-6 hours post-transfusion and 8-12 hours post-transfusion) vs the pre-transfusion level.
Interventions
- BIOLOGICAL Transfusion of red blood cells
- BIOLOGICAL Infusion of albumin/saline
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2013-12 |
| Est. Completion | 2018-12 |
What the finished NCT02087553 record still lists
NCT02087553 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 2 interventions - of which Transfusion of red blood cells is the first listed.
NCT02087553 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02087553 about?
NCT02087553 is a clinical study titled "PICU Transfusion Study: Harmful Effects of Red Blood Cell Transfusions". The investigators hypothesize that the storage-damaged red cells are responsible for some of the adverse effects of transfusion. In this observational study, the investigators will measure various laboratory parameters both before and after transfusion in a pediatric intensive care unit to determine...
What is the current status of trial NCT02087553?
This trial is currently completed. The enrollment target is 120 participants. The study started on 2013-12. Estimated completion is 2018-12.
What interventions are being tested in trial NCT02087553?
The interventions under investigation include: Transfusion of red blood cells (BIOLOGICAL), Infusion of albumin/saline (BIOLOGICAL).
Who is sponsoring clinical trial NCT02087553?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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