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NCT02060188 · ClinicalTrials.gov registry record · Phase 2

A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 2
Development phase
385
Enrollment target

NCT02060188: Completed Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT02060188 is a Phase 2 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 385 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (189% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02060188, a Phase 2 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 2
Development phase
385 participants
Enrollment target

Study Summary

The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in meaningful tumor size reduction, in participants with colon cancer that has come back or has spread, and who have a specific biomarker in their tumors.

Primary Outcome

Objective Response Rate (ORR) is defined as the number of randomized participants who achieve a best overall response (BOR) of confirmed complete response (CR) or confirmed partial response (PR), based on investigator assessments \\\[using Response Evaluation Criteria in Solid Tumors (RECIST) v1.1\\\], divided by the number of all randomized participants. Complete Response (CR): Disappearance of all target lesions. Any pathological lymph nodes (whether target or non-target) must have reduction

Interventions

  • DRUG Nivolumab
  • DRUG Ipilimumab
  • DRUG Daratumumab
  • DRUG Cobimetinib
  • DRUG BMS-986016

Trial Details

FieldValue
Enrollment Target 385 participants
Start Date 2014-03-12
Est. Completion 2024-10-22
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

What the finished NCT02060188 record still lists

NCT02060188 is an interventional study that assigns participants to a tested intervention. The registered 385 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (189% higher).

The record links to 0 conditions, and to 5 interventions - of which Nivolumab is the first listed.

NCT02060188 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02060188 about?

NCT02060188 is a clinical study titled "A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread". The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in meaningful tumor size reduction, in participants with colon cancer that has come back or has spread, and who have a specific biomarker in their tumors.

What is the current status of trial NCT02060188?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 385 participants. The study started on 2014-03-12. Estimated completion is 2024-10-22.

What interventions are being tested in trial NCT02060188?

The interventions under investigation include: Nivolumab (DRUG), Ipilimumab (DRUG), Daratumumab (DRUG), Cobimetinib (DRUG), BMS-986016 (DRUG).

Who is sponsoring clinical trial NCT02060188?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02060188's enrollment target sits among peer trials

385 109th of 2000 higher than 1,890 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02060188, the US trial registry maintained by the National Library of Medicine. NCT02060188 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.