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NCT02057458 · ClinicalTrials.gov registry record · Phase 2
Blood Flow and Vascular Function in Cystic Fibrosis
A Phase 2 study of Cystic Fibrosis, sponsored by Augusta University.
- Completed
- Registry status
- Phase 2
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT02057458 is a Phase 2 study of Cystic Fibrosis that has completed, run by Augusta University. The registered enrollment target is 19 participants, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state.
The verdict
NCT02057458, a Phase 2 study of Cystic Fibrosis, has completed, sponsored by Augusta University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
Cystic fibrosis (CF) has many health consequences. A reduction in the ability to perform exercise in patients with CF is related to greater death rates, steeper decline in lung function, and more frequent lung infections. However, the physiological mechanisms for this reduced exercise capacity are unknown. The investigators laboratory recently published the first evidence of systemic vascular dysfunction in patients with CF. Therefore, it is reasonable to suspect that the blood vessels are involved with exercise intolerance in CF. This study will look at how 1) blood flow and 2) artery function contribute to exercise capacity in CF.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Sildenafil (Acute-1 hour)
- DRUG Sildenafil (Subchronic-4 weeks)
Study Locations (1)
Georgia
- Augusta University - Augusta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2014-04 |
| Est. Completion | 2018-07 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02057458
The ClinicalTrials.gov registry entry for NCT02057458 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 179-participant average among 169 other Cystic Fibrosis trials with a reported enrollment target (89% lower). The listed sponsor is Augusta University, which has 106 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Cystic Fibrosis appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT02057458 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.
Frequently Asked Questions
What is clinical trial NCT02057458 about?
NCT02057458 is a clinical study titled "Blood Flow and Vascular Function in Cystic Fibrosis". Cystic fibrosis (CF) has many health consequences. A reduction in the ability to perform exercise in patients with CF is related to greater death rates, steeper decline in lung function, and more frequent lung infections. However, the physiological mechanisms for this reduced exercise capacity are u...
What is the current status of trial NCT02057458?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2014-04. Estimated completion is 2018-07.
What conditions does trial NCT02057458 study?
This clinical trial studies the following conditions: Cystic Fibrosis.
What interventions are being tested in trial NCT02057458?
The interventions under investigation include: Placebo (DRUG), Sildenafil (Acute-1 hour) (DRUG), Sildenafil (Subchronic-4 weeks) (DRUG).
Who is sponsoring clinical trial NCT02057458?
This trial is sponsored by Augusta University, which has 106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02057458 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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