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NCT02057354 · ClinicalTrials.gov registry record · NA
Neuroimaging Study of Exercise and Memory Function
A NA study, sponsored by Boston University.
- Completed
- Registry status
- NA
- Development phase
- 190
- Enrollment target
NCT02057354: Completed NA study, sponsored by Boston University.
NCT02057354 is a NA study that has completed, run by Boston University. The registered enrollment target is 190 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02057354, a NA study, has completed, sponsored by Boston University.
- COMPLETED
- Registry status
- NA
- Development phase
- 190 participants
- Enrollment target
Study Summary
The investigators are examining the effects of exercise and cardiovascular fitness on cognitive processes, brain function, and the amount of several proteins in the blood. These proteins include a hormone called cortisol, also known as the "stress hormone," and a growth factor called "brain-derived neurotrophic factor" (BDNF). The "stress hormone" cortisol is produced by the adrenal glands. Stress, exercise, obesity, and other factors may influence cortisol levels. BDNF is a protein that promotes the health of nerve cells in the brain and in the body. It plays a role in the growth, maturation, and maintenance of these cells. The amount of this protein in blood samples is therefore an indicator of healthy nerve cell function. Here, the investigators are investigating if exercise improves brain function by changing BDNF levels. Participation in this research study will take approximately 4 months. During this time, participants will make four initial study visits. The first visit is for informed consent and screening, the second and third visits are for baseline fitness testing, and the fourth visit is for a blood draw, cognitive testing, and a functional Magnetic Resonance Imaging (fMRI) exam. Functional MRI is a brain imaging technique that uses a magnetic field to "take pictures" of the brain while a person performs a given task. It will take up to approximately three weeks to complete these initial four study visits. Following the four initial study visits, the exercise-training program will begin. Participants will be randomized to one of two training programs: an aerobic exercise program and a non-aerobic exercise program consisting of strengthening, balance and stretching exercises. The exercise training program will last 12 weeks. There will be three one-hour exercise sessions per week. After completion of the exercise-training program, participants will attend three follow-up study visits. The first two follow-up visits are for fitness testing. The third and
Primary Outcome
Measurement of brain activity during task performance and measurement of change in regional brain volumes.
Interventions
- BEHAVIORAL Aerobic Exercise
- BEHAVIORAL Non-Aerobic Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2014-04 |
| Est. Completion | 2018-03 |
| Phase | NA |
What the finished NCT02057354 record still lists
NCT02057354 is an interventional study that assigns participants to a tested intervention. The registered 190 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 2 interventions - of which Aerobic Exercise is the first listed.
NCT02057354 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02057354 about?
NCT02057354 is a clinical study titled "Neuroimaging Study of Exercise and Memory Function". The investigators are examining the effects of exercise and cardiovascular fitness on cognitive processes, brain function, and the amount of several proteins in the blood. These proteins include a hormone called cortisol, also known as the "stress hormone," and a growth factor called "brain-derived ...
What is the current status of trial NCT02057354?
This trial is currently completed. It is a NA study. The enrollment target is 190 participants. The study started on 2014-04. Estimated completion is 2018-03.
What interventions are being tested in trial NCT02057354?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL), Non-Aerobic Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT02057354?
This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02057354's enrollment target sits among peer trials
190 574th of 2000 higher than 1,425 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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