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NCT02056249 · ClinicalTrials.gov registry record
Evaluation of the Effect of Hypoglycemia With PET and a Norepinephrine Transporter Ligand
A clinical trial, sponsored by Yale University.
- Completed
- Registry status
- 9
- Enrollment target
NCT02056249: Completed study, sponsored by Yale University.
NCT02056249 is a clinical trial that has completed, run by Yale University. The registered enrollment target is 9 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02056249 has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- 9 participants
- Enrollment target
Study Summary
The aim of this study is to use Positron Emission Tomography (PET) imaging to measure changes in norepinephrine transporter (NET) concentrations in the brain and periphery of healthy individuals during hypoglycemia. We hypothesize that during hypoglycemia, NE levels will increase within the brain, especially the hypothalamus, and this likely contributes to activation of glucose counterregulatory responses. We further hypothesize that during hypoglycemia, NET concentrations in key glucoregulatory regions will change in order to sustain or prolong sympathetic nervous system activation of counterregulatory responses.
Primary Outcome
An IV catheter may be inserted in the other hand to allow drawing of continuous blood for measurement of tracer kinetics. PET scans will be done as subjects rest, the tracer will be injected, and initial data will be acquired on the scanner.
Interventions
- OTHER Norepinephrine Transporter (NET) ligand
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2011-06 |
| Est. Completion | 2017-06 |
What the finished NCT02056249 record still lists
NCT02056249 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 9 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Norepinephrine Transporter (NET) ligand is the first listed.
NCT02056249 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02056249 about?
NCT02056249 is a clinical study titled "Evaluation of the Effect of Hypoglycemia With PET and a Norepinephrine Transporter Ligand". The aim of this study is to use Positron Emission Tomography (PET) imaging to measure changes in norepinephrine transporter (NET) concentrations in the brain and periphery of healthy individuals during hypoglycemia. We hypothesize that during hypoglycemia, NE levels will increase within the brain, ...
What is the current status of trial NCT02056249?
This trial is currently completed. The enrollment target is 9 participants. The study started on 2011-06. Estimated completion is 2017-06.
What interventions are being tested in trial NCT02056249?
The interventions under investigation include: Norepinephrine Transporter (NET) ligand (OTHER).
Who is sponsoring clinical trial NCT02056249?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
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