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NCT02055365 · ClinicalTrials.gov registry record · NA
Pilot Study: Gene Expression Profiling of Immune Response to HBV Vaccination in Healthy Volunteers
A NA study, sponsored by Rockefeller University.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT02055365: Completed NA study, sponsored by Rockefeller University.
NCT02055365 is a NA study that has completed, run by Rockefeller University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02055365, a NA study, has completed, sponsored by Rockefeller University.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Vaccines have been responsible for preventing millions of deaths and extending the average human lifespan. Effective vaccines stimulate the cells of the immune system to activate genes and associated functions that bring about protective immunity.This study aims to define cellular functions and genes important for the hepatitis B (HBV) vaccine immune response in healthy individuals. The investigators hypothesize that many genes associated with innate and adaptive immune functions are important for an effective HBV vaccine response.
Primary Outcome
Number of differentially expressed genes at time point versus prevaccination baseline (p\<0.05). Following Principal Components Analysis, data from one participant series was identified as a technical outlier and excluded from downstream analyses. Differential gene expression analysis was conducted with the voom/limma tools in the R statistical framework.
Interventions
- BIOLOGICAL Hepatitis B Vaccine (Recombinant)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2014-02-18 |
| Est. Completion | 2015-01-06 |
| Phase | NA |
What the finished NCT02055365 record still lists
NCT02055365 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Hepatitis B Vaccine (Recombinant) is the first listed.
NCT02055365 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02055365 about?
NCT02055365 is a clinical study titled "Pilot Study: Gene Expression Profiling of Immune Response to HBV Vaccination in Healthy Volunteers". Vaccines have been responsible for preventing millions of deaths and extending the average human lifespan. Effective vaccines stimulate the cells of the immune system to activate genes and associated functions that bring about protective immunity.This study aims to define cellular functions and gene...
What is the current status of trial NCT02055365?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2014-02-18. Estimated completion is 2015-01-06.
What interventions are being tested in trial NCT02055365?
The interventions under investigation include: Hepatitis B Vaccine (Recombinant) (BIOLOGICAL).
Who is sponsoring clinical trial NCT02055365?
This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02055365's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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