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NCT02051595 · ClinicalTrials.gov registry record · Early Phase 1

The Effects of Modified Ultrafiltration on Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery

A Early Phase 1 study, sponsored by University of Florida.

Completed
Registry status
Early Phase 1
Development phase
25
Enrollment target

NCT02051595: Completed Early Phase 1 study, sponsored by University of Florida.

NCT02051595 is a Early Phase 1 study that has completed, run by University of Florida. The registered enrollment target is 25 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02051595, a Early Phase 1 study, has completed, sponsored by University of Florida.

COMPLETED
Registry status
Early Phase 1
Development phase
25 participants
Enrollment target

Study Summary

Antibiotics are routinely used to prevent surgical wound infection. Vancomycin is a widely used antibiotic for surgery in patients with an allergy to penicillin. During cardiac surgery, cardiopulmonary bypass (CPB) and modified ultrafiltration (MUF) are routinely used and can lower the level of the antibiotic. The purpose of this study is to quantify the change in plasma vancomycin concentration associated with cardiopulmonary bypass and modified ultrafiltration.

Primary Outcome

Blood samples to monitor the vancomycin concentration will be collected at several time points during surgery.

Interventions

  • OTHER Vancomycin concentrations

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2014-04
Est. Completion 2015-04
Phase Early Phase 1
University of Florida

1,106 total trials

What the finished NCT02051595 record still lists

NCT02051595 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (53% lower).

The record links to 0 conditions, and to 1 intervention - of which Vancomycin concentrations is the first listed.

NCT02051595 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02051595 about?

NCT02051595 is a clinical study titled "The Effects of Modified Ultrafiltration on Vancomycin Levels During Cardiopulmonary Bypass in Cardiac Surgery". Antibiotics are routinely used to prevent surgical wound infection. Vancomycin is a widely used antibiotic for surgery in patients with an allergy to penicillin. During cardiac surgery, cardiopulmonary bypass (CPB) and modified ultrafiltration (MUF) are routinely used and can lower the level of the ...

What is the current status of trial NCT02051595?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 25 participants. The study started on 2014-04. Estimated completion is 2015-04.

What interventions are being tested in trial NCT02051595?

The interventions under investigation include: Vancomycin concentrations (OTHER).

Who is sponsoring clinical trial NCT02051595?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02051595's enrollment target sits among peer trials

25 1000th of 2000 higher than 965 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02051595, the US trial registry maintained by the National Library of Medicine. NCT02051595 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.