Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02042898 · ClinicalTrials.gov registry record · NA

Transfusion Requirements in Cardiac Surgery III

A NA study, sponsored by Unity Health Toronto.

Completed
Registry status
NA
Development phase
5,028
Enrollment target

NCT02042898: Completed NA study, sponsored by Unity Health Toronto.

NCT02042898 is a NA study that has completed, run by Unity Health Toronto. The registered enrollment target is 5,028 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (258% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02042898, a NA study, has completed, sponsored by Unity Health Toronto.

COMPLETED
Registry status
NA
Development phase
5,028 participants
Enrollment target

Study Summary

TRICS-III is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in high risk patients having cardiac surgery using a non-inferiority trial design.

Primary Outcome

Composite score of any one of the following events occurring during the index hospitalization (from the start of surgery until hospital discharge or postoperative day 28, whichever comes first): (1) all-cause mortality; (2) myocardial infarction; (3) new renal failure requiring dialysis; or (4) new focal neurological deficit

Interventions

  • OTHER Restrictive Transfusion Strategy
  • OTHER Liberal transfusion strategy

Trial Details

FieldValue
Enrollment Target 5,028 participants
Start Date 2014-01-20
Est. Completion 2017-10-01
Phase NA
Unity Health Toronto

12 total trials

What the finished NCT02042898 record still lists

NCT02042898 is an interventional study that assigns participants to a tested intervention. Its 5,028 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (258% higher).

The record links to 0 conditions, and to 2 interventions - of which Restrictive Transfusion Strategy is the first listed.

NCT02042898 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02042898 about?

NCT02042898 is a clinical study titled "Transfusion Requirements in Cardiac Surgery III". TRICS-III is an international, multi-centre, open-label randomized controlled trial of two commonly used transfusion strategies in high risk patients having cardiac surgery using a non-inferiority trial design.

What is the current status of trial NCT02042898?

This trial is currently completed. It is a NA study. The enrollment target is 5,028 participants. The study started on 2014-01-20. Estimated completion is 2017-10-01.

What interventions are being tested in trial NCT02042898?

The interventions under investigation include: Restrictive Transfusion Strategy (OTHER), Liberal transfusion strategy (OTHER).

Who is sponsoring clinical trial NCT02042898?

This trial is sponsored by Unity Health Toronto, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02042898's enrollment target sits among peer trials

5,028 25th of 2000 higher than 1,976 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04743362 · 5,010 participants

    A Study of Noninvasive Methods to Evaluate Skin and Mucosal Conditions

  • NCT07037459 · 5,056 participants · Phase 3

    Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • NCT00060541 · 5,000 participants

    Evaluation and Treatment of Neurosurgical Disorders

  • NCT00575081 · 5,000 participants

    Physiological Brain Atlas Development

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02042898, the US trial registry maintained by the National Library of Medicine. NCT02042898 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.