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NCT02039765 · ClinicalTrials.gov registry record · Phase 1

Pharmacokinetics and Safety of Topical Administration of Brimonidine Tartrate Ophthalmic Solution 0.025%.

A Phase 1 study, sponsored by Bausch & Lomb Incorporated.

Completed
Registry status
Phase 1
Development phase
12
Enrollment target

NCT02039765: Completed Phase 1 study, sponsored by Bausch & Lomb Incorporated.

NCT02039765 is a Phase 1 study that has completed, run by Bausch & Lomb Incorporated. The registered enrollment target is 12 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02039765, a Phase 1 study, has completed, sponsored by Bausch & Lomb Incorporated.

COMPLETED
Registry status
Phase 1
Development phase
12 participants
Enrollment target

Study Summary

To characterize the plasma pharmacokinetics and safety profile of brimonidine following a single dose and 4 times per day (QID) dosing of brimonidine tartrate ophthalmic solution 0.025% for 7 days in healthy, adult subjects.

Primary Outcome

Blood samples will be collected for the determination of brimonidine in plasma at the specified time points on Day 1.

Interventions

  • DRUG Brimonidine tartrate

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2014-02
Est. Completion 2014-04
Phase Phase 1
Bausch & Lomb Incorporated

174 total trials

What the finished NCT02039765 record still lists

NCT02039765 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (80% lower).

The record links to 0 conditions, and to 1 intervention - of which Brimonidine tartrate is the first listed.

NCT02039765 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02039765 about?

NCT02039765 is a clinical study titled "Pharmacokinetics and Safety of Topical Administration of Brimonidine Tartrate Ophthalmic Solution 0.025%.". To characterize the plasma pharmacokinetics and safety profile of brimonidine following a single dose and 4 times per day (QID) dosing of brimonidine tartrate ophthalmic solution 0.025% for 7 days in healthy, adult subjects.

What is the current status of trial NCT02039765?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants. The study started on 2014-02. Estimated completion is 2014-04.

What interventions are being tested in trial NCT02039765?

The interventions under investigation include: Brimonidine tartrate (DRUG).

Who is sponsoring clinical trial NCT02039765?

This trial is sponsored by Bausch & Lomb Incorporated, which has 174 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02039765's enrollment target sits among peer trials

12 1852nd of 2000 higher than 90 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02039765, the US trial registry maintained by the National Library of Medicine. NCT02039765 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.