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NCT02038166 · ClinicalTrials.gov registry record
Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis
A clinical trial of Rhinosinusitis, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- 20
- Enrollment target
- 1
- Study location
NCT02038166: Recruiting study of Rhinosinusitis, sponsored by University of Alabama at Birmingham.
NCT02038166 is a study of Rhinosinusitis that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02038166, a study of Rhinosinusitis, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to determine if acquired (partial) Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) deficiency contributes substantially to the pathogenic mechanisms underlying Chronic Rhinosinusitis (CRS), creating a localized environment that impairs mucociliary clearance (MCC).
Primary Outcome
A \>-5 mV increase in total chloride secretion (change in NPD following nominal Cl- solution + amiloride + isoproterenol) is typically designated as evidence of measurable difference in CFTR function. Results of NPD measurements between CRS patients and healthy controls will be examined.
Conditions Studied
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2015-01 |
| Est. Completion | 2027-12 |
What NCT02038166 shows while recruiting
NCT02038166 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 20 participants, a relatively small participant target.
The record links to 1 condition, with Rhinosinusitis appearing as the primary indexed condition, and to 0 interventions.
NCT02038166 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT02038166 about?
NCT02038166 is a clinical study titled "Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis". The purpose of this study is to determine if acquired (partial) Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) deficiency contributes substantially to the pathogenic mechanisms underlying Chronic Rhinosinusitis (CRS), creating a localized environment that impairs mucociliary clearance (M...
What is the current status of trial NCT02038166?
This trial is currently recruiting. The enrollment target is 20 participants. The study started on 2015-01. Estimated completion is 2027-12.
What conditions does trial NCT02038166 study?
This clinical trial studies the following conditions: Rhinosinusitis.
Who is sponsoring clinical trial NCT02038166?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02038166 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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