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NCT02032277 · ClinicalTrials.gov registry record · Phase 3
A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carboplatin to Standard Chemotherapy Versus Standard Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer
A Phase 3 study, sponsored by AbbVie.
- Completed
- Registry status
- Phase 3
- Development phase
- 634
- Enrollment target
NCT02032277: Completed Phase 3 study, sponsored by AbbVie.
NCT02032277 is a Phase 3 study that has completed, run by AbbVie. The registered enrollment target is 634 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02032277, a Phase 3 study, has completed, sponsored by AbbVie.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 634 participants
- Enrollment target
Study Summary
This is a 3 arm Phase 3 study to evaluate the safety and efficacy of the addition of veliparib plus carboplatin versus the addition of carboplatin to standard neoadjuvant chemotherapy versus standard neoadjuvant chemotherapy in subjects with early stage TNBC.
Primary Outcome
Pathological complete response (pCR) in the breast tissue and the lymph node tissue will be assessed upon completion of pre-operative systemic therapy and definitive surgery.
Interventions
- DRUG Cyclophosphamide
- DRUG Carboplatin
- DRUG Placebo
- DRUG Doxorubicin
- DRUG Paclitaxel
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 634 participants |
| Start Date | 2014-04-02 |
| Est. Completion | 2020-11-12 |
| Phase | Phase 3 |
What the finished NCT02032277 record still lists
NCT02032277 is an interventional study that assigns participants to a tested intervention. The registered 634 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (18% lower).
The record links to 0 conditions, and to 5 interventions - of which Cyclophosphamide is the first listed.
NCT02032277 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02032277 about?
NCT02032277 is a clinical study titled "A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carboplatin to Standard Chemotherapy Versus Standard Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer". This is a 3 arm Phase 3 study to evaluate the safety and efficacy of the addition of veliparib plus carboplatin versus the addition of carboplatin to standard neoadjuvant chemotherapy versus standard neoadjuvant chemotherapy in subjects with early stage TNBC.
What is the current status of trial NCT02032277?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 634 participants. The study started on 2014-04-02. Estimated completion is 2020-11-12.
What interventions are being tested in trial NCT02032277?
The interventions under investigation include: Cyclophosphamide (DRUG), Carboplatin (DRUG), Placebo (DRUG), Doxorubicin (DRUG), Paclitaxel (DRUG).
Who is sponsoring clinical trial NCT02032277?
This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02032277's enrollment target sits among peer trials
634 579th of 2000 higher than 1,421 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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