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NCT02020343 · ClinicalTrials.gov registry record
Insulin Resistance in the Control of Intestinal Lipid Metabolism
A clinical trial, sponsored by University of Missouri-Columbia.
- Completed
- Registry status
- 22
- Enrollment target
NCT02020343 is a clinical trial that has completed, run by University of Missouri-Columbia. The registered enrollment target is 22 participants.
The verdict
NCT02020343 has completed, sponsored by University of Missouri-Columbia.
- COMPLETED
- Registry status
- 22 participants
- Enrollment target
Study Summary
America's preferential consumption of high-fat/high-sugar foods is a driving force in the current epidemic of obesity and insulin resistance. Recent scientific observations suggest that the taste of food may play a role in how the body processes the food eaten in a meal. The intestine may play a central role in all aspects of dietary fat metabolism, from initial encounter with taste buds in the mouth to eventual triglyceride (TG) storage in the body. The investigators hypothesize that elevated blood fats in insulin resistance are a result of elevated intestinal-TG secretion and poor communication of this organ to the rest of the body after meals. In this study, meal feeding and sensory studies will be performed to determine whether the mechanism of taste-associated intestinal signaling leads to higher levels of blood fats after meals in 24 healthy, insulin resistant and type 2 diabetic subjects. Individuals will consume special meals the night before the tests and participate in sensory tests in the morning to analyze the effect of taste. The goal of this work is to understand how insulin resistance may cause impaired signaling between the taste buds and the intestine to result in an elevation in blood lipids, which increases the risk for other chronic diseases. This study will generate data for a future study to understand how diabetes treatment affects this process.
Interventions
- BEHAVIORAL taste tests
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2014-01 |
| Est. Completion | 2016-08 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02020343
The ClinicalTrials.gov registry entry for NCT02020343 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 22 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Missouri-Columbia, which has 291 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which taste tests is the first listed.
NCT02020343 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02020343 about?
NCT02020343 is a clinical study titled "Insulin Resistance in the Control of Intestinal Lipid Metabolism". America's preferential consumption of high-fat/high-sugar foods is a driving force in the current epidemic of obesity and insulin resistance. Recent scientific observations suggest that the taste of food may play a role in how the body processes the food eaten in a meal. The intestine may play a cen...
What is the current status of trial NCT02020343?
This trial is currently completed. The enrollment target is 22 participants. The study started on 2014-01. Estimated completion is 2016-08.
What interventions are being tested in trial NCT02020343?
The interventions under investigation include: taste tests (BEHAVIORAL).
Who is sponsoring clinical trial NCT02020343?
This trial is sponsored by University of Missouri-Columbia, which has 291 total clinical trials registered on ClinicalTrials.gov.
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