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NCT02006407 · ClinicalTrials.gov registry record · NA
A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors
A NA study, sponsored by University of Michigan Rogel Cancer Center.
- Terminated
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT02006407: Clinical Trial NA study, sponsored by University of Michigan Rogel Cancer Center.
NCT02006407 is a NA study that was terminated before completion, run by University of Michigan Rogel Cancer Center. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02006407, a NA study, was terminated before completion, sponsored by University of Michigan Rogel Cancer Center.
- TERMINATED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
This is a pilot study to assess the changes in white matter, in the brain, in response to radiation therapy and correlate these changes with later declines in cognitive function.
Primary Outcome
Descriptive statistics and plots will be used to determine Diffusion Tensor Imaging (DTI) parameters for various regions in the brain. The mean (across subject) change in DTI parameter for a given region, at a given time, will be used to assess white matter injury.
Interventions
- RADIATION Cranial Radiotherapy
- DEVICE MRI with Diffusion Tensor Imaging (DTI)
- BEHAVIORAL Neuro-cognitive Testing (CogState)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2013-06 |
| Est. Completion | 2015-12 |
| Phase | NA |
Why NCT02006407 stopped before completion
NCT02006407 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which Cranial Radiotherapy is the first listed.
NCT02006407 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02006407 about?
NCT02006407 is a clinical study titled "A Pilot Study to Evaluate Neurocognitive Injury and Longitudinal Changes in White Matter During Radiation Therapy in Children With Primary Brain Tumors". This is a pilot study to assess the changes in white matter, in the brain, in response to radiation therapy and correlate these changes with later declines in cognitive function.
What is the current status of trial NCT02006407?
This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2013-06. Estimated completion is 2015-12.
What interventions are being tested in trial NCT02006407?
The interventions under investigation include: Cranial Radiotherapy (RADIATION), MRI with Diffusion Tensor Imaging (DTI) (DEVICE), Neuro-cognitive Testing (CogState) (BEHAVIORAL).
Who is sponsoring clinical trial NCT02006407?
This trial is sponsored by University of Michigan Rogel Cancer Center, which has 292 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02006407's enrollment target sits among peer trials
5 1988th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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