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NCT01992432 · ClinicalTrials.gov registry record

Brain Functional MRI in Older Women With Breast Cancer (Brain fMRI-BC)

A clinical trial of Breast Cancer, sponsored by City of Hope Medical Center.

Active
Registry status
49
Enrollment target
2
Study locations

NCT01992432: Active study of Breast Cancer, sponsored by City of Hope Medical Center.

NCT01992432 is a study of Breast Cancer that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 49 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01992432, a study of Breast Cancer, is active but no longer recruiting, sponsored by City of Hope Medical Center.

ACTIVE NOT RECRUITING
Registry status
49 participants
Enrollment target
2
Study locations

Study Summary

This study will use advanced MRI techniques to characterize the changes that occur to the structure and functionality of the brain in older breast cancer patients receiving adjuvant chemotherapy, and determine the relationship between the brain changes and severity of chemotherapy toxicity. Our results will be an early step towards identifying neuroimaging markers of aging, breast cancer and chemotherapy treatment, and will contribute to our understanding of the underlying pathophysiology of cognitive changes and chemotherapy toxicity in vulnerable, older adults with cancer. Furthermore, the work will lay the foundation for future, larger scale clinical studies of cognitive changes and chemotherapy toxicity in the aging cancer population.

Primary Outcome

Prior to and after chemotherapy in older patients with breast cancer.

Conditions Studied

Study Locations (2)

California

  • City of Hope Medical Center - Duarte
  • South Pasadena Cancer Center - South Pasadena

Trial Details

FieldValue
Enrollment Target 49 participants
Start Date 2013-09-30
Est. Completion 2026-11-30
City of Hope Medical Center

582 total trials

What the registry record for NCT01992432 still lists

NCT01992432 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 0 interventions.

NCT01992432 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT01992432 about?

NCT01992432 is a clinical study titled "Brain Functional MRI in Older Women With Breast Cancer (Brain fMRI-BC)". This study will use advanced MRI techniques to characterize the changes that occur to the structure and functionality of the brain in older breast cancer patients receiving adjuvant chemotherapy, and determine the relationship between the brain changes and severity of chemotherapy toxicity. Our resu...

What is the current status of trial NCT01992432?

This trial is currently active not recruiting. The enrollment target is 49 participants. The study started on 2013-09-30. Estimated completion is 2026-11-30.

What conditions does trial NCT01992432 study?

This clinical trial studies the following conditions: Breast Cancer.

Who is sponsoring clinical trial NCT01992432?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01992432 being conducted?

This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01992432's enrollment target sits among peer trials

49 816th of 1224 higher than 405 of 1,224 other Breast Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01992432, the US trial registry maintained by the National Library of Medicine. NCT01992432 (small enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.