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NCT01989273 · ClinicalTrials.gov registry record
Detection and Management of Non-Compressible Hemorrhage by Vena Cava Ultrasonography
A clinical trial, sponsored by University of California, San Diego.
- Completed
- Registry status
- 121
- Enrollment target
NCT01989273: Completed study, sponsored by University of California, San Diego.
NCT01989273 is a clinical trial that has completed, run by University of California, San Diego. The registered enrollment target is 121 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01989273 has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- 121 participants
- Enrollment target
Study Summary
This is a study of patients admitted with major traumatic injuries. Such patients may develop inadequate circulation to the organs as a result of internal blood loss. Early detection of internal blood loss can be difficult as physical examination alone may miss patients with significant blood loss. Some patients with internal bleeding will arrive with low blood pressure; these patients are usually given 2 liters of intravenous fluid to determine if their blood pressure will recover. If the blood pressure does not rise or if it drops again later, the blood loss can be assumed to be severe, and the patient will likely need transfusions, surgery and other interventions. However, this fluid treatment method can lead to delays and complications as some patients may initially respond but then continue to bleed. The inferior vena cava (IVC) is the large vein draining blood from the lower body to the heart. The inferior vena cava is known to empty when the patient has had significant blood loss. The vena cava diameter can be seen using ultrasound. This study intends to perform ultrasound to examine the vena cava diameter on patients just after arriving with major trauma. The hypothesis of the proposed study is that an ultrasound assessment protocol of inferior vena cava diameter and collapsibility can detect and aid management of non-compressible hemorrhage in major trauma victims. After the patient has been given the 2 liter intravenous fluid treatment, the inferior vena cava diameter will be measured again. A third examination 8-24 hours after admission will determine if the inferior vena cava diameter has returned to normal. We propose that measuring the inferior vena cava in this manner can predict those patients who are likely to continue bleeding and require interventions such as surgery. Early detection in these patients may avoid delays in treatment, complications and excess mortality. Because this examination is done with handheld ultrasound machines, it could be d
Interventions
- DEVICE Ultrasound of inferior vena cava
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2012-08 |
| Est. Completion | 2018-03-01 |
What the finished NCT01989273 record still lists
NCT01989273 is an observational study that tracks outcomes without assigning an intervention. The registered 121 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Ultrasound of inferior vena cava is the first listed.
NCT01989273 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01989273 about?
NCT01989273 is a clinical study titled "Detection and Management of Non-Compressible Hemorrhage by Vena Cava Ultrasonography". This is a study of patients admitted with major traumatic injuries. Such patients may develop inadequate circulation to the organs as a result of internal blood loss. Early detection of internal blood loss can be difficult as physical examination alone may miss patients with significant blood loss. ...
What is the current status of trial NCT01989273?
This trial is currently completed. The enrollment target is 121 participants. The study started on 2012-08. Estimated completion is 2018-03-01.
What interventions are being tested in trial NCT01989273?
The interventions under investigation include: Ultrasound of inferior vena cava (DEVICE).
Who is sponsoring clinical trial NCT01989273?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
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