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NCT01984710 · ClinicalTrials.gov registry record · NA
Deep Brain Stimulation for Treatment Resistant Depression With the Medtronic Activa PC+S
A NA study of Treatment-Resistant Depression, sponsored by Emory University.
- Active
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT01984710: Active NA study of Treatment-Resistant Depression, sponsored by Emory University.
NCT01984710 is a NA study of Treatment-Resistant Depression that is active but no longer recruiting, run by Emory University. The registered enrollment target is 10 participants, below the 374-participant average among 54 other Treatment-Resistant Depression trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01984710, a NA study of Treatment-Resistant Depression, is active but no longer recruiting, sponsored by Emory University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to use the Activa Primary Cell + Sensing (PC+S) device to study Latent Field Potential (LFP) in the brains of people with Treatment Resistant Depression (TRD) before and during active stimulation. The ultimate goal is to understand the neural network that causes TRD and the changes that DBS cause in that network that results in the antidepressant effects.
Primary Outcome
Electrophysiological changes in response to stimulation will be quantified. Continuous Activa PC+S Local Field Potential (LFP) recordings will be monitored from Day 1 post-op until the battery is depleted, which is anticipated to be after approximately 2-3 years.
Conditions Studied
Interventions
- DEVICE Medtronic Activa PC+S System
Study Locations (1)
Georgia
- Emory University - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2013-09 |
| Est. Completion | 2029-01 |
| Phase | NA |
What the registry record for NCT01984710 still lists
NCT01984710 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 374-participant average among 54 other Treatment-Resistant Depression trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Treatment-Resistant Depression appearing as the primary indexed condition, and to 1 intervention - of which Medtronic Activa PC+S System is the first listed.
NCT01984710 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT01984710 about?
NCT01984710 is a clinical study titled "Deep Brain Stimulation for Treatment Resistant Depression With the Medtronic Activa PC+S". The goal of this study is to use the Activa Primary Cell + Sensing (PC+S) device to study Latent Field Potential (LFP) in the brains of people with Treatment Resistant Depression (TRD) before and during active stimulation. The ultimate goal is to understand the neural network that causes TRD and the...
What is the current status of trial NCT01984710?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2013-09. Estimated completion is 2029-01.
What conditions does trial NCT01984710 study?
This clinical trial studies the following conditions: Treatment-Resistant Depression.
What interventions are being tested in trial NCT01984710?
The interventions under investigation include: Medtronic Activa PC+S System (DEVICE).
Who is sponsoring clinical trial NCT01984710?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01984710 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Treatment-Resistant Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01984710's enrollment target sits among peer trials
10 49th of 54 higher than 3 of 54 other Treatment-Resistant Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Treatment-Resistant Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Ultrasound Neuromodulation of Circuits and Negative Valence Systems in Treatment-Resistant Depression
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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
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PCS in Severe Treatment Resistant Depression
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Accelerated Intermittent Theta-Burst Stimulation (aiTBS) in Treatment-Resistant Depression of Bipolar II Disorder
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