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NCT01978574 · ClinicalTrials.gov registry record · NA
Intellectual Enrichment to Build Cognitive Reserve in MS
A NA study, sponsored by Kessler Foundation.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT01978574: Completed NA study, sponsored by Kessler Foundation.
NCT01978574 is a NA study that has completed, run by Kessler Foundation. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01978574, a NA study, has completed, sponsored by Kessler Foundation.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
Cognitive problems are a primary concern for people with multiple sclerosis. In many cases, people with MS report these issues to be more debilitating than the motor symptoms that are targeted by most treatment strategies. For people with MS, impaired memory and thinking skills can interfere with the ability to function efficiently in multiple professional and personal roles. Finding ways to decrease, slow, or reverse declines in memory and thinking skills is a vitally important research priority. We now know that engaging in intellectually enriching activities helps protect against the negative impact of MS disease-related declines in memory and thinking. Such activities contribute to something called 'cognitive reserve,' which serves as a protection against disease-related declines in memory and thinking. Thus far, no one has created a treatment that aims to provide a concentrated 'dose' of intellectual enrichment to build cognitive reserve. The present intervention aims to do precisely this. Here, we have developed a program of enriching activities that are delivered via a personal iPad. This allows for a 12-week 'treatment' that is entirely home-based, while also providing close personal contact between participants and our study personnel, who will communicate daily via emails. Week by week, participants choose from a menu of intellectually enriching activities such that their treatment is dynamic and customizable to fit their interests. The intervention is designed to be fun, as we hope the activities will be incorporated into people's lives beyond the period of the study itself. Given what we already know about the striking benefits of cognitive reserve to protect against disease-related declines in cognitive functioning, we expect to show that treatment with a daily, intense, intellectually enriching schedule of activities results in improved thinking and memory for people with MS. We will also investigate the positive impact of our treatment on the brains o
Interventions
- BEHAVIORAL Intellectual Enrichment daily activities
- BEHAVIORAL Intellectual Enrichment documentary videos
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2013-06-01 |
| Est. Completion | 2014-06-01 |
| Phase | NA |
What the finished NCT01978574 record still lists
NCT01978574 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Intellectual Enrichment daily activities is the first listed.
NCT01978574 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01978574 about?
NCT01978574 is a clinical study titled "Intellectual Enrichment to Build Cognitive Reserve in MS". Cognitive problems are a primary concern for people with multiple sclerosis. In many cases, people with MS report these issues to be more debilitating than the motor symptoms that are targeted by most treatment strategies. For people with MS, impaired memory and thinking skills can interfere with th...
What is the current status of trial NCT01978574?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2013-06-01. Estimated completion is 2014-06-01.
What interventions are being tested in trial NCT01978574?
The interventions under investigation include: Intellectual Enrichment daily activities (BEHAVIORAL), Intellectual Enrichment documentary videos (BEHAVIORAL).
Who is sponsoring clinical trial NCT01978574?
This trial is sponsored by Kessler Foundation, which has 104 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01978574's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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