Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01973283 · ClinicalTrials.gov registry record · Phase 4
Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
A Phase 4 study, sponsored by New York State Psychiatric Institute.
- Completed
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
NCT01973283 is a Phase 4 study that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 100 participants.
The verdict
NCT01973283, a Phase 4 study, has completed, sponsored by New York State Psychiatric Institute.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
Study Summary
The goal of this open-administration treatment study of citalopram (or duloxetine) is to evaluate the effect of antidepressant medication on treating the syndrome of "frailty" in older adults with depressive symptoms. Patients with significant depressive symptoms (defined as CES-D (Center for Epidemiological Studies - Depression scale) \> 10) and 1 or more symptoms of the frailty syndrome (exhaustion, decreased energy, weight loss, decreased grip strength, and slow/unsteady gait) will be evaluated and treated with citalopram (or duloxetine) for 8 weeks to test whether antidepressant medication improves both the syndrome of frailty and depressive symptoms. Patients evaluated at the Adult and Late Life Depression clinic and eligible to participate in the study will be treated with an antidepressant medication and assessed on the primary outcome variables (characteristics of frailty, depressive symptoms) as well as on secondary variables which include cognition (global cognition, episodic memory, executive function), and function (physical mobility, instrumental activities of daily living, and social functioning) prior to treatment initiation and following 8-weeks of treatment. The hypotheses for this protocol predict that we will discover a significant improvement on both frailty characteristics and depressive symptoms in this clinical population when treated with antidepressant medication (citalopram or duloxetine).
Interventions
- DRUG Antidepressant Medication
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2014-02-19 |
| Est. Completion | 2020-12-05 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01973283
The ClinicalTrials.gov registry entry for NCT01973283 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is New York State Psychiatric Institute, which has 364 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Antidepressant Medication is the first listed.
NCT01973283 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01973283 about?
NCT01973283 is a clinical study titled "Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults". The goal of this open-administration treatment study of citalopram (or duloxetine) is to evaluate the effect of antidepressant medication on treating the syndrome of "frailty" in older adults with depressive symptoms. Patients with significant depressive symptoms (defined as CES-D (Center for Epidem...
What is the current status of trial NCT01973283?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2014-02-19. Estimated completion is 2020-12-05.
What interventions are being tested in trial NCT01973283?
The interventions under investigation include: Antidepressant Medication (DRUG).
Who is sponsoring clinical trial NCT01973283?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.