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NCT01965106 · ClinicalTrials.gov registry record · Phase 2

Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)

A Phase 2 study, sponsored by Quark Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
46
Enrollment target

NCT01965106: Completed Phase 2 study, sponsored by Quark Pharmaceuticals.

NCT01965106 is a Phase 2 study that has completed, run by Quark Pharmaceuticals. The registered enrollment target is 46 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01965106, a Phase 2 study, has completed, sponsored by Quark Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
46 participants
Enrollment target

Study Summary

This study will assess any side effects that may occur when QPI-1007 is injected into the eye in subjects with acute primary angle-closure glaucoma, as well as how long it takes for the body to clear the drug. This study will also test whether QPI-1007, injected into the eye, helps prevent both structural damage of the nerve tissue in the eye and the loss of visual function in subjects with acute primary angle-closure glaucoma.

Interventions

  • DRUG QPI-1007 Injection
  • DRUG (including placebo)

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2013-12
Est. Completion 2015-07
Phase Phase 2
Quark Pharmaceuticals

14 total trials

What the finished NCT01965106 record still lists

NCT01965106 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 2 interventions - of which QPI-1007 Injection is the first listed.

NCT01965106 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01965106 about?

NCT01965106 is a clinical study titled "Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)". This study will assess any side effects that may occur when QPI-1007 is injected into the eye in subjects with acute primary angle-closure glaucoma, as well as how long it takes for the body to clear the drug. This study will also test whether QPI-1007, injected into the eye, helps prevent both stru...

What is the current status of trial NCT01965106?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 46 participants. The study started on 2013-12. Estimated completion is 2015-07.

What interventions are being tested in trial NCT01965106?

The interventions under investigation include: QPI-1007 Injection (DRUG), (including placebo) (DRUG).

Who is sponsoring clinical trial NCT01965106?

This trial is sponsored by Quark Pharmaceuticals, which has 14 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01965106's enrollment target sits among peer trials

46 1286th of 2000 higher than 705 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01965106, the US trial registry maintained by the National Library of Medicine. NCT01965106 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.