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NCT01952288 · ClinicalTrials.gov registry record · Phase 4

Simvastatin for mTBI

A Phase 4 study, sponsored by VA Office of Research and Development.

Completed
Registry status
Phase 4
Development phase
5
Enrollment target

NCT01952288: Completed Phase 4 study, sponsored by VA Office of Research and Development.

NCT01952288 is a Phase 4 study that has completed, run by VA Office of Research and Development. The registered enrollment target is 5 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01952288, a Phase 4 study, has completed, sponsored by VA Office of Research and Development.

COMPLETED
Registry status
Phase 4
Development phase
5 participants
Enrollment target

Study Summary

Study of simvastatin in Iraq/Afghanistan Veterans with multiple blast exposure and mTBI. The study will measure substances in cerebrospinal fluid (CSF) that are related to dementing disorders.

Primary Outcome

Change in CSF total tau concentration from baseline to 12 months of study drug treatment

Interventions

  • DRUG Placebo Oral Tablet
  • DRUG simvastatin

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2013-09-16
Est. Completion 2017-06-20
Phase Phase 4
VA Office of Research and Development

1,668 total trials

What the finished NCT01952288 record still lists

NCT01952288 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo Oral Tablet is the first listed.

NCT01952288 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01952288 about?

NCT01952288 is a clinical study titled "Simvastatin for mTBI". Study of simvastatin in Iraq/Afghanistan Veterans with multiple blast exposure and mTBI. The study will measure substances in cerebrospinal fluid (CSF) that are related to dementing disorders.

What is the current status of trial NCT01952288?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 5 participants. The study started on 2013-09-16. Estimated completion is 2017-06-20.

What interventions are being tested in trial NCT01952288?

The interventions under investigation include: Placebo Oral Tablet (DRUG), simvastatin (DRUG).

Who is sponsoring clinical trial NCT01952288?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01952288's enrollment target sits among peer trials

5 1989th of 2000 higher than 7 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01952288, the US trial registry maintained by the National Library of Medicine. NCT01952288 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.