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NCT01951950 · ClinicalTrials.gov registry record · Phase 1
Nicardipine vs Esmolol Craniotomy Emergence
A Phase 1 study of Brain Tumors, sponsored by Northwestern University.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT01951950: Completed Phase 1 study of Brain Tumors, sponsored by Northwestern University.
NCT01951950 is a Phase 1 study of Brain Tumors that has completed, run by Northwestern University. The registered enrollment target is 40 participants, below the 6,339-participant average among 10 other Brain Tumors trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01951950, a Phase 1 study of Brain Tumors, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Emergence hypertension is a common occurrence in patients emerging from general anesthesia. This elevation of arterial pressure is particularly concerning in patients undergoing craniotomy due to increased risk of morbidity and mortality in patients with altered intracranial elastance. Thus, identifying better methods to attenuate the hemodynamic changes associated with emergence from anesthesia can improve patient safety, especially in the neurosurgical patient. Study Hypothesis: Nicardipine is more effective than esmolol as a sole agent in maintaining blood pressure within goal range in the setting of emergence hypertension after craniotomy.
Conditions Studied
Interventions
- DRUG Nicardipine
- DRUG Esmolol
Study Locations (1)
Illinois
- Northwestern Memorial Hospital - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2013-09 |
| Est. Completion | 2014-05 |
| Phase | Phase 1 |
What the finished NCT01951950 record still lists
NCT01951950 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 6,339-participant average among 10 other Brain Tumors trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Brain Tumors appearing as the primary indexed condition, and to 2 interventions - of which Nicardipine is the first listed.
NCT01951950 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT01951950 about?
NCT01951950 is a clinical study titled "Nicardipine vs Esmolol Craniotomy Emergence". Emergence hypertension is a common occurrence in patients emerging from general anesthesia. This elevation of arterial pressure is particularly concerning in patients undergoing craniotomy due to increased risk of morbidity and mortality in patients with altered intracranial elastance. Thus, identif...
What is the current status of trial NCT01951950?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2013-09. Estimated completion is 2014-05.
What conditions does trial NCT01951950 study?
This clinical trial studies the following conditions: Brain Tumors.
What interventions are being tested in trial NCT01951950?
The interventions under investigation include: Nicardipine (DRUG), Esmolol (DRUG).
Who is sponsoring clinical trial NCT01951950?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01951950 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01951950's enrollment target sits among peer trials
40 9th of 10 higher than 2 of 10 other Brain Tumors trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Tumors trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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