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NCT01946074 · ClinicalTrials.gov registry record · Phase 1
A Study of ABT-165 in Subjects With Solid Tumors
A Phase 1 study, sponsored by AbbVie.
- Completed
- Registry status
- Phase 1
- Development phase
- 101
- Enrollment target
NCT01946074: Completed Phase 1 study, sponsored by AbbVie.
NCT01946074 is a Phase 1 study that has completed, run by AbbVie. The registered enrollment target is 101 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01946074, a Phase 1 study, has completed, sponsored by AbbVie.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 101 participants
- Enrollment target
Study Summary
This is a Phase 1/1b open-label study evaluating the safety, pharmacokinetics (PK), and preliminary efficacy of ABT-165 when administered as monotherapy and in combination with paclitaxel or 5-fluoruracil, folinic acid and irinotecan (FOLFIRI) or ABBV-181 with/without paclitaxel in subjects with advanced solid tumors. Enrollment to Cohorts A, B were completed and for Cohorts C and D are recruiting.
Primary Outcome
Hematology, Chemistry, and Urinalysis
Interventions
- DRUG FOLFIRI
- DRUG paclitaxel
- DRUG ABBV-181
- DRUG ABT-165
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2013-08-08 |
| Est. Completion | 2022-09-28 |
| Phase | Phase 1 |
What the finished NCT01946074 record still lists
NCT01946074 is an interventional study that assigns participants to a tested intervention. The registered 101 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% higher).
The record links to 0 conditions, and to 4 interventions - of which FOLFIRI is the first listed.
NCT01946074 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01946074 about?
NCT01946074 is a clinical study titled "A Study of ABT-165 in Subjects With Solid Tumors". This is a Phase 1/1b open-label study evaluating the safety, pharmacokinetics (PK), and preliminary efficacy of ABT-165 when administered as monotherapy and in combination with paclitaxel or 5-fluoruracil, folinic acid and irinotecan (FOLFIRI) or ABBV-181 with/without paclitaxel in subjects with adv...
What is the current status of trial NCT01946074?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 101 participants. The study started on 2013-08-08. Estimated completion is 2022-09-28.
What interventions are being tested in trial NCT01946074?
The interventions under investigation include: FOLFIRI (DRUG), paclitaxel (DRUG), ABBV-181 (DRUG), ABT-165 (DRUG).
Who is sponsoring clinical trial NCT01946074?
This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01946074's enrollment target sits among peer trials
101 546th of 2000 higher than 1,455 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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