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NCT01943799 · ClinicalTrials.gov registry record · Phase 2
Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B
A Phase 2 study, sponsored by Gilead Sciences.
- Completed
- Registry status
- Phase 2
- Development phase
- 178
- Enrollment target
NCT01943799: Completed Phase 2 study, sponsored by Gilead Sciences.
NCT01943799 is a Phase 2 study that has completed, run by Gilead Sciences. The registered enrollment target is 178 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (34% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01943799, a Phase 2 study, has completed, sponsored by Gilead Sciences.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 178 participants
- Enrollment target
Study Summary
The primary objectives of this study are to evaluate the safety and efficacy of GS-4774 in adults with chronic hepatitis B (CHB) viral infection who have been virally suppressed with an oral antiviral (OAV) medication.
Primary Outcome
The change from baseline to Week 24 in HBsAg was analyzed using a mixed effect model for repeated measures (MMRM). The model included included treatment, HBsAg baseline level (≤ 1000 IU/mL or \> 1000 IU/mL), HBeAg baseline status (positive or negative), visit, and treatment-by-visit interaction as fixed effects and visit as a repeated measure.
Interventions
- BIOLOGICAL GS-4774
- DRUG OAV Regimen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 178 participants |
| Start Date | 2013-09-13 |
| Est. Completion | 2015-03-03 |
| Phase | Phase 2 |
What the finished NCT01943799 record still lists
NCT01943799 is an interventional study that assigns participants to a tested intervention. The registered 178 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (34% higher).
The record links to 0 conditions, and to 2 interventions - of which GS-4774 is the first listed.
NCT01943799 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01943799 about?
NCT01943799 is a clinical study titled "Safety and Efficacy of GS-4774 for the Treatment of Chronic Hepatitis B". The primary objectives of this study are to evaluate the safety and efficacy of GS-4774 in adults with chronic hepatitis B (CHB) viral infection who have been virally suppressed with an oral antiviral (OAV) medication.
What is the current status of trial NCT01943799?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 178 participants. The study started on 2013-09-13. Estimated completion is 2015-03-03.
What interventions are being tested in trial NCT01943799?
The interventions under investigation include: GS-4774 (BIOLOGICAL), OAV Regimen (DRUG).
Who is sponsoring clinical trial NCT01943799?
This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01943799's enrollment target sits among peer trials
178 391st of 2000 higher than 1,607 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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