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NCT01940471 · ClinicalTrials.gov registry record · Phase 3
Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen
A Phase 3 study, sponsored by Gilead Sciences.
- Completed
- Registry status
- Phase 3
- Development phase
- 875
- Enrollment target
NCT01940471: Completed Phase 3 study, sponsored by Gilead Sciences.
NCT01940471 is a Phase 3 study that has completed, run by Gilead Sciences. The registered enrollment target is 875 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (13% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01940471, a Phase 3 study, has completed, sponsored by Gilead Sciences.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 875 participants
- Enrollment target
Study Summary
The primary objective of this study is to compare the efficacy, safety, and tolerability of tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate (TDF) in treatment-naive and treatment-experienced adults with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B virus (HBV) infection.
Interventions
- DRUG TAF
- DRUG TDF
- DRUG TDF Placebo
- DRUG TAF Placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 875 participants |
| Start Date | 2013-09-11 |
| Est. Completion | 2022-10-13 |
| Phase | Phase 3 |
What the finished NCT01940471 record still lists
NCT01940471 is an interventional study that assigns participants to a tested intervention. The registered 875 participants enrollment target is mid-sized for trials with a published cap, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (13% higher).
The record links to 0 conditions, and to 4 interventions - of which TAF is the first listed.
NCT01940471 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01940471 about?
NCT01940471 is a clinical study titled "Study to Compare Tenofovir Alafenamide (TAF) Versus Tenofovir Disoproxil Fumarate (TDF) in Participants With Chronic Hepatitis B Infection Who Are Positive for Hepatitis B e Antigen". The primary objective of this study is to compare the efficacy, safety, and tolerability of tenofovir alafenamide (TAF) versus tenofovir disoproxil fumarate (TDF) in treatment-naive and treatment-experienced adults with hepatitis B e antigen (HBeAg)-positive chronic hepatitis B virus (HBV) infection...
What is the current status of trial NCT01940471?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 875 participants. The study started on 2013-09-11. Estimated completion is 2022-10-13.
What interventions are being tested in trial NCT01940471?
The interventions under investigation include: TAF (DRUG), TDF (DRUG), TDF Placebo (DRUG), TAF Placebo (DRUG).
Who is sponsoring clinical trial NCT01940471?
This trial is sponsored by Gilead Sciences, which has 504 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01940471's enrollment target sits among peer trials
875 372nd of 2000 higher than 1,629 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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