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NCT01928771 · ClinicalTrials.gov registry record · Phase 3
Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled Asthma
A Phase 3 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 3
- Development phase
- 2,681
- Enrollment target
NCT01928771: Completed Phase 3 study, sponsored by AstraZeneca.
NCT01928771 is a Phase 3 study that has completed, run by AstraZeneca. The registered enrollment target is 2,681 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (247% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01928771, a Phase 3 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 2,681 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether Benralizumab reduces the number of asthma exacerbations in patients who remain uncontrolled on high doses of ICS-LABA.
Primary Outcome
The annual exacerbation rate is based on unadjudicated annual exacerbation rate reported by the investigator in the eCRF
Interventions
- BIOLOGICAL Placebo
- BIOLOGICAL Benralizumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,681 participants |
| Start Date | 2013-09-19 |
| Est. Completion | 2016-04-05 |
| Phase | Phase 3 |
What the finished NCT01928771 record still lists
NCT01928771 is an interventional study that assigns participants to a tested intervention. Its 2,681 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (247% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01928771 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01928771 about?
NCT01928771 is a clinical study titled "Efficacy and Safety Study of Benralizumab Added to High-dose Inhaled Corticosteroid Plus LABA in Patients With Uncontrolled Asthma". The purpose of this study is to determine whether Benralizumab reduces the number of asthma exacerbations in patients who remain uncontrolled on high doses of ICS-LABA.
What is the current status of trial NCT01928771?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 2,681 participants. The study started on 2013-09-19. Estimated completion is 2016-04-05.
What interventions are being tested in trial NCT01928771?
The interventions under investigation include: Placebo (BIOLOGICAL), Benralizumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT01928771?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01928771's enrollment target sits among peer trials
2,681 84th of 2000 higher than 1,917 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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