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NCT01926899 · ClinicalTrials.gov registry record · Phase 1

A Multicenter Phase I Study Evaluating the Addition of Bortezomib to an Established Acute Graft Versus Host Disease Prophylaxis Regimen in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients

A Phase 1 study, sponsored by Indiana University.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target

NCT01926899: Completed Phase 1 study, sponsored by Indiana University.

NCT01926899 is a Phase 1 study that has completed, run by Indiana University. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01926899, a Phase 1 study, has completed, sponsored by Indiana University.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target

Study Summary

The objective of this study is to determine the maximum tolerated dose (MTD) of bortezomib in combination with calcineurin inhibitor and methotrexate as acute graft versus host disease (aGVHD) prophylaxis in pediatric patients undergoing allogeniec hematopoietic stem cell transplant (alloHSCT)

Interventions

  • DRUG Bortezomib administration

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2013-08-01
Est. Completion 2018-03-15
Phase Phase 1
Indiana University

890 total trials

What the finished NCT01926899 record still lists

NCT01926899 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).

The record links to 0 conditions, and to 1 intervention - of which Bortezomib administration is the first listed.

NCT01926899 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01926899 about?

NCT01926899 is a clinical study titled "A Multicenter Phase I Study Evaluating the Addition of Bortezomib to an Established Acute Graft Versus Host Disease Prophylaxis Regimen in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Patients". The objective of this study is to determine the maximum tolerated dose (MTD) of bortezomib in combination with calcineurin inhibitor and methotrexate as acute graft versus host disease (aGVHD) prophylaxis in pediatric patients undergoing allogeniec hematopoietic stem cell transplant (alloHSCT)

What is the current status of trial NCT01926899?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2013-08-01. Estimated completion is 2018-03-15.

What interventions are being tested in trial NCT01926899?

The interventions under investigation include: Bortezomib administration (DRUG).

Who is sponsoring clinical trial NCT01926899?

This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01926899's enrollment target sits among peer trials

15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01926899, the US trial registry maintained by the National Library of Medicine. NCT01926899 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.