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NCT01924273 · ClinicalTrials.gov registry record · Phase 1

Novel Treatment for Port Wine Stain Birthmarks

A Phase 1 study, sponsored by University of California, Irvine.

Completed
Registry status
Phase 1
Development phase
7
Enrollment target

NCT01924273: Completed Phase 1 study, sponsored by University of California, Irvine.

NCT01924273 is a Phase 1 study that has completed, run by University of California, Irvine. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01924273, a Phase 1 study, has completed, sponsored by University of California, Irvine.

COMPLETED
Registry status
Phase 1
Development phase
7 participants
Enrollment target

Study Summary

Port wine stains Birthmark are congenital, progressive vascular malformations of the skin that occur in approximately 0.7% of newborns. Approximately 1.5 million individuals in the United States and 32 million people worldwide have Port wine stains birthmarks. Two-thirds of these malformations occur on the face. Personality development of virtually all patients is adversely affected as a result of the negative reaction of others to a "marked" person. Detailed studies have documented lower self-esteem and difficulties with interpersonal interactions in Port wine stains patients. Port wine stains are initially flat and red, but with time, they tend to darken to purple and become thickened as vascular nodules develop. This thickening occurs in approximately two-thirds of lesions and further disfigures the facial features of many patients.

Primary Outcome

The outcome measure will be PWS blanching as assessed by Diffuse Reflectance Imaging/Laser Speckle Imaging/Spatial Frequency Domain Imaging.

Interventions

  • DRUG Talaporfin sodium

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2013-06
Est. Completion 2017-07-03
Phase Phase 1
University of California, Irvine

368 total trials

What the finished NCT01924273 record still lists

NCT01924273 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).

The record links to 0 conditions, and to 1 intervention - of which Talaporfin sodium is the first listed.

NCT01924273 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01924273 about?

NCT01924273 is a clinical study titled "Novel Treatment for Port Wine Stain Birthmarks". Port wine stains Birthmark are congenital, progressive vascular malformations of the skin that occur in approximately 0.7% of newborns. Approximately 1.5 million individuals in the United States and 32 million people worldwide have Port wine stains birthmarks. Two-thirds of these malformations occur...

What is the current status of trial NCT01924273?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2013-06. Estimated completion is 2017-07-03.

What interventions are being tested in trial NCT01924273?

The interventions under investigation include: Talaporfin sodium (DRUG).

Who is sponsoring clinical trial NCT01924273?

This trial is sponsored by University of California, Irvine, which has 368 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01924273's enrollment target sits among peer trials

7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01924273, the US trial registry maintained by the National Library of Medicine. NCT01924273 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.