Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01915823 · ClinicalTrials.gov registry record · Phase 3

Safety and Efficacy Trial of Dymista Nasal Spray in Children Ages 4 to 11 With Seasonal Allergic Rhinitis (SAR)

A Phase 3 study, sponsored by Meda Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
348
Enrollment target

NCT01915823: Completed Phase 3 study, sponsored by Meda Pharmaceuticals.

NCT01915823 is a Phase 3 study that has completed, run by Meda Pharmaceuticals. The registered enrollment target is 348 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01915823, a Phase 3 study, has completed, sponsored by Meda Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
348 participants
Enrollment target

Study Summary

The purpose of this study is to determine if Dymista nasal spray is better and safer than placebo in treating children ages 4 to \<12 years old who have seasonal allergic rhinitis.

Primary Outcome

change from baseline in AM+PM rTNSS (reflective total nasal symptoms score): ITT( intent to treat population)change from baseline in 12-hour reflective total nasal symptom score (rTNSS) consisting of nasal congestion,runny nose, itchy nose and sneezing scored twice daily (AM and PM) in diary for the entire 14 day study period.The measurement scale is 0 to 24 so that the higher the number the worse the symptom.A reduction in symptom severity score is indicated by a negative value.A greater negati

Interventions

  • DRUG azelastine hydrochloride and fluticasone propionate
  • DRUG Dymista vehicle

Trial Details

FieldValue
Enrollment Target 348 participants
Start Date 2013-07
Phase Phase 3
Meda Pharmaceuticals

19 total trials

What the finished NCT01915823 record still lists

NCT01915823 is an interventional study that assigns participants to a tested intervention. The registered 348 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 2 interventions - of which azelastine hydrochloride and fluticasone propionate is the first listed.

NCT01915823 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01915823 about?

NCT01915823 is a clinical study titled "Safety and Efficacy Trial of Dymista Nasal Spray in Children Ages 4 to 11 With Seasonal Allergic Rhinitis (SAR)". The purpose of this study is to determine if Dymista nasal spray is better and safer than placebo in treating children ages 4 to \<12 years old who have seasonal allergic rhinitis.

What is the current status of trial NCT01915823?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 348 participants. The study started on 2013-07.

What interventions are being tested in trial NCT01915823?

The interventions under investigation include: azelastine hydrochloride and fluticasone propionate (DRUG), Dymista vehicle (DRUG).

Who is sponsoring clinical trial NCT01915823?

This trial is sponsored by Meda Pharmaceuticals, which has 19 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01915823's enrollment target sits among peer trials

348 1045th of 2000 higher than 953 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04041479 · 348 participants · Phase 3

    Biomarker-guided rTMS for Treatment Resistant Depression

  • NCT04530565 · 348 participants · Phase 3

    Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults

  • NCT05428735 · 348 participants · NA

    The DRAGON 2 Trial

  • NCT05787379 · 348 participants · NA

    Care for Veterans Post-COVID-19

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01915823, the US trial registry maintained by the National Library of Medicine. NCT01915823 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.