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NCT01914952 · ClinicalTrials.gov registry record · NA
Alternate Dosing Strategies for Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation: Effect on Plasma HMB Responses
A NA study, sponsored by Metabolic Technologies.
- Completed
- Registry status
- NA
- Development phase
- 11
- Enrollment target
NCT01914952 is a NA study that has completed, run by Metabolic Technologies. The registered enrollment target is 11 participants.
The verdict
NCT01914952, a NA study, has completed, sponsored by Metabolic Technologies.
- COMPLETED
- Registry status
- NA
- Development phase
- 11 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the rise in plasma Beta-hydroxy-beta-methylbutyrate (HMB) after the dietary supplement has been administered in different forms. Prior studies have indicated that form of administration affects bioavailability of the HMB supplement. Therefore the current study will examine the bioavailability of a single dose of HMB given as: * 1.0g CaHMB in gelatin capsule * 0.8 g HMB free acid in a gelcap * 0.8 g HMB free acid in water * 1.0 g CaHMB in water * 0.8 g HMB free acid The randomized study will be a crossover design and each study subject will undergo the experimental protocol for each of the supplementation forms. Because of the different administration forms, the study will be an open label study. Briefly, the fasted participants will report to the laboratory in the morning. After an initial blood sample is taken, the dose of HMB will be administered. Blood will then be samples at 2, 5, 10, 15, 25, 35, 45, 60, 90, 120, 180, 360, 720, and 1440 min post administration. A 24 h complete urine collection will also be performed. Participants will be given a light sack lunch 4 h after administration of the dosage and will remain at the laboratory through the 360 min sampling. Participants will then be allowed to leave the laboratory and return for the 720 min sampling after which the participants can eat an normal evening meal. Participants will return to the laboratory fasted the next morning for the final sample. A minimum 48 h washout period will be required before the next dosage form is administered and the process repeated.
Interventions
- DIETARY_SUPPLEMENT CaHMB capsule
- DIETARY_SUPPLEMENT HMB free acid gelcap
- DIETARY_SUPPLEMENT HMB free acid mixed in water
- DIETARY_SUPPLEMENT CaHMB in water
- DIETARY_SUPPLEMENT HMB free acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2013-05 |
| Est. Completion | 2014-05 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01914952
The ClinicalTrials.gov registry entry for NCT01914952 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Metabolic Technologies, which has 16 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which CaHMB capsule is the first listed.
NCT01914952 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01914952 about?
NCT01914952 is a clinical study titled "Alternate Dosing Strategies for Beta-hydroxy-beta-methylbutyrate (HMB) Supplementation: Effect on Plasma HMB Responses". The purpose of this study is to examine the rise in plasma Beta-hydroxy-beta-methylbutyrate (HMB) after the dietary supplement has been administered in different forms. Prior studies have indicated that form of administration affects bioavailability of the HMB supplement. Therefore the current study...
What is the current status of trial NCT01914952?
This trial is currently completed. It is a NA study. The enrollment target is 11 participants. The study started on 2013-05. Estimated completion is 2014-05.
What interventions are being tested in trial NCT01914952?
The interventions under investigation include: CaHMB capsule (DIETARY_SUPPLEMENT), HMB free acid gelcap (DIETARY_SUPPLEMENT), HMB free acid mixed in water (DIETARY_SUPPLEMENT), CaHMB in water (DIETARY_SUPPLEMENT), HMB free acid (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01914952?
This trial is sponsored by Metabolic Technologies, which has 16 total clinical trials registered on ClinicalTrials.gov.
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