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NCT01910792 · ClinicalTrials.gov registry record · NA

Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery

A NA study of Vitamin D Deficiency and Gastrointestinal Diseases, sponsored by Boston University.

Completed
Registry status
NA
Development phase
19
Enrollment target
1
Study location

NCT01910792 is a NA study of Vitamin D Deficiency and Gastrointestinal Diseases that has completed, run by Boston University. The registered enrollment target is 19 participants, below the 275-participant average among 48 other Vitamin D Deficiency trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01910792, a NA study of Vitamin D Deficiency and Gastrointestinal Diseases, has completed, sponsored by Boston University.

COMPLETED
Registry status
NA
Development phase
19 participants
Enrollment target
1
Study location

Study Summary

Patients with fat malabsorption due to Crohn's disease, ulcerative colitis, or other causes including cystic fibrosis, among others, or who have undergone gastric bypass have increased incidence of vitamin D deficiency relative to the general population. Given that vitamin D is fat soluble and absorbed in the proximal small intestine, it has been documented that vitamin D deficiency in people with a fat malabsorption syndrome is due to decreased absorption of vitamin D. The amount of vitamin D produced from winter sunlight (in Boston, MA) and dietary sources will negligibly raise blood vitamin D levels in these patients, and oral vitamin D supplementation may have limited efficacy due to malabsorption. A variety of UV light sources have been developed and sold as in-home tanning devices and to produce vitamin D in reptiles. The efficacy of correcting vitamin D deficiency by the skin exposure to an artificial source of UVB radiation in patients with fat malabsorption syndromes (Crohn's disease, ulcerative colitis, or cystic fibrosis) or after gastric bypass surgery has not been studied. The investigators have conducted a pilot study in healthy adults that demonstrated that exposure to the lamp raised the blood level of 25-hydroxyvitamin D with no side effects. The main purpose of this study is to evaluate the effect of the FDA approved artificial source of ultraviolet (UVB) radiation (Sperti® lamp) in improving vitamin D status in patients with fat malabsorption syndromes and patients who have undergone roux-en-Y gastric bypass surgery.

Interventions

  • DEVICE Sperti Lamp

Study Locations (1)

Massachusetts

  • Boston Medical Center - Boston

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2011-03
Est. Completion 2014-02
Phase NA

Sponsor

Boston University

185 total trials

What the Registry Record Tells You About NCT01910792

The ClinicalTrials.gov registry entry for NCT01910792 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 275-participant average among 48 other Vitamin D Deficiency trials with a reported enrollment target (93% lower). The listed sponsor is Boston University, which has 185 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Vitamin D Deficiency appearing as the primary indexed condition, and to 1 intervention - of which Sperti Lamp is the first listed.

NCT01910792 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT01910792 about?

NCT01910792 is a clinical study titled "Ultraviolet Light And Vitamin D In Subjects With Fat Malabsorption Or After Gastric Bypass Surgery". Patients with fat malabsorption due to Crohn's disease, ulcerative colitis, or other causes including cystic fibrosis, among others, or who have undergone gastric bypass have increased incidence of vitamin D deficiency relative to the general population. Given that vitamin D is fat soluble and absor...

What is the current status of trial NCT01910792?

This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2011-03. Estimated completion is 2014-02.

What conditions does trial NCT01910792 study?

This clinical trial studies the following conditions: Vitamin D Deficiency, Gastrointestinal Diseases.

What interventions are being tested in trial NCT01910792?

The interventions under investigation include: Sperti Lamp (DEVICE).

Who is sponsoring clinical trial NCT01910792?

This trial is sponsored by Boston University, which has 185 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01910792 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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