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NCT01909895 · ClinicalTrials.gov registry record · NA
Study of the Effects of Negative Emotions on Endothelial Function
A NA study, sponsored by Columbia University.
- Completed
- Registry status
- NA
- Development phase
- 280
- Enrollment target
NCT01909895: Completed NA study, sponsored by Columbia University.
NCT01909895 is a NA study that has completed, run by Columbia University. The registered enrollment target is 280 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01909895, a NA study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- NA
- Development phase
- 280 participants
- Enrollment target
Study Summary
Study aims and hypotheses are as follows: Primary Hypotheses: Compared to the neutral condition, the anger recall task will acutely induce endothelial dysfunction by impairing endothelium-dependent arterial vasodilation (Hypothesis 1a); increasing circulating levels of EC-derived microparticles (EMPs), a marker of EC injury (Hypothesis 1b); and reducing circulating levels of bone marrow-derived endothelial progenitor cells (EPCs), a marker of EC reparative capacity (Hypothesis 1c). Secondary Hypotheses: Compared to the neutral condition, the depressed mood and separately the anxiety recall tasks will acutely impair endothelium-dependent arterial vasodilation, increase circulating levels of EMPs, and reduce circulating levels of bone marrow-derived EPCs. There will be a relation of the level of self-reported anger, depressed mood, and anxiety with endothelial dysfunction.
Interventions
- OTHER Anger Induction
- OTHER Depressed Mood Induction
- OTHER Anxiety Induction
- OTHER Neutral emotion task
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 280 participants |
| Start Date | 2013-09-01 |
| Est. Completion | 2020-11-01 |
| Phase | NA |
What the finished NCT01909895 record still lists
NCT01909895 is an interventional study that assigns participants to a tested intervention. The registered 280 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (80% lower).
The record links to 0 conditions, and to 4 interventions - of which Anger Induction is the first listed.
NCT01909895 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01909895 about?
NCT01909895 is a clinical study titled "Study of the Effects of Negative Emotions on Endothelial Function". Study aims and hypotheses are as follows: Primary Hypotheses: Compared to the neutral condition, the anger recall task will acutely induce endothelial dysfunction by impairing endothelium-dependent arterial vasodilation (Hypothesis 1a); increasing circulating levels of EC-derived microparticles (E...
What is the current status of trial NCT01909895?
This trial is currently completed. It is a NA study. The enrollment target is 280 participants. The study started on 2013-09-01. Estimated completion is 2020-11-01.
What interventions are being tested in trial NCT01909895?
The interventions under investigation include: Anger Induction (OTHER), Depressed Mood Induction (OTHER), Anxiety Induction (OTHER), Neutral emotion task (OTHER).
Who is sponsoring clinical trial NCT01909895?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01909895's enrollment target sits among peer trials
280 380th of 2000 higher than 1,620 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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